A Novel Longitudinal Proteomic Aging Index Predicts Mortality, Multimorbidity, and Frailty in Older Adults.

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Title: A Novel Longitudinal Proteomic Aging Index Predicts Mortality, Multimorbidity, and Frailty in Older Adults.
Authors: Rao Z; Division of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, Minnesota, USA., Wang S; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA., Li A; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA., Blaha MJ; Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Coresh J; Departments of Population Health and Medicine, NYU Grossman School of Medicine, New York, New York, USA., Ganz P; Division of Cardiology, Zuckerberg San Francisco General Hospital and Department of Medicine, University of California, San Francisco, California, USA., Marshall CH; Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA., Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA., Platz EA; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Post W; Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA., Sedaghat S; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA., Whelton SP; Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Prizment A; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA., Guan W; Division of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, Minnesota, USA.
Source: Aging cell [Aging Cell] 2026 Jan; Vol. 25 (1), pp. e70317. Date of Electronic Publication: 2025 Dec 08.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-9726
DOI:10.1111/acel.70317