Procyanidin Suppresses Tumor Growth by Activating the B-Cell MAPK Pathway through Remodulation of the Gut Microbiota and Metabolites in Hepatocellular Carcinoma.

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Title: Procyanidin Suppresses Tumor Growth by Activating the B-Cell MAPK Pathway through Remodulation of the Gut Microbiota and Metabolites in Hepatocellular Carcinoma.
Authors: Huo R; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Clinical Laboratory, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China., Gu CZ; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Liu Y; Department of Pancreatic and Gastrointestinal Surgery Division, Ningbo No.2 Hospital, Ningbo, China.; Ningbo Key Laboratory of Intestinal Microecology and Human Major Diseases, Ningbo, China., Wei ZX; Department of Hepatobiliary and Pancreatic Surgery, Qunli Branch, the First Afiliated Hospital of Harbin Medical University, Harbin, China., Liu T; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Zhu J; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Ding L; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Liu Y; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Wang CY; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Li YN; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., He XY; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Yang WJ; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Wang BL; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Laboratory Medicine, Shanghai Geriatric Medical Center, Shanghai, China.; Department of Laboratory Medicine, Wusong Branch, Zhongshan Hospital, Fudan University, Shanghai, China.; Cancer Center, Shanghai Zhongshan Hospital, Fudan University, Shanghai, China., Wei YW; Department of Pancreatic and Gastrointestinal Surgery Division, Ningbo No.2 Hospital, Ningbo, China.; Ningbo Key Laboratory of Intestinal Microecology and Human Major Diseases, Ningbo, China., Guo W; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Laboratory Medicine, Shanghai Geriatric Medical Center, Shanghai, China.; Department of Laboratory Medicine, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, China.; Department of Laboratory Medicine, Wusong Branch, Zhongshan Hospital, Fudan University, Shanghai, China.; Cancer Center, Shanghai Zhongshan Hospital, Fudan University, Shanghai, China.
Source: International journal of biological sciences [Int J Biol Sci] 2026 Jan 01; Vol. 22 (1), pp. 161-177. Date of Electronic Publication: 2026 Jan 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1449-2288
DOI:10.7150/ijbs.113217