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Predicting prolonged dalbavancin exposure using machine learning: a validated strategy for individualized redosing.

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Title: Predicting prolonged dalbavancin exposure using machine learning: a validated strategy for individualized redosing.
Authors: Sayadi H; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France., Gregoire M; Clinical Pharmacology Department, Nantes University, Nantes University Hospital, Nantes, France.; Nantes University, Nantes University Hospital, Infection and Immunity: Targets and Drugs, IICiMed, UR 1155, Nantes, France., Fromage Y; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France., Ksentini M; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France., Labriffe M; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France., Monchaud C; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France., Codde C; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.; Department of Infectious and Tropical Diseases, Dupuytren University Hospital (CHU Dupuytren), Limoges, France., Faucher J-F; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.; Department of Infectious and Tropical Diseases, Dupuytren University Hospital (CHU Dupuytren), Limoges, France., Boutoille D; Infectious and Tropical Diseases Department, Nantes University, Nantes University Hospital, INSERM, CIC 1413, Nantes, France., Marquet P; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France., Woillard J-B; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2026 Jan 07; Vol. 70 (1), pp. e0136325. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Sayadi+H%22">Sayadi H</searchLink>; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Gregoire+M%22">Gregoire M</searchLink>; Clinical Pharmacology Department, Nantes University, Nantes University Hospital, Nantes, France.; Nantes University, Nantes University Hospital, Infection and Immunity: Targets and Drugs, IICiMed, UR 1155, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Fromage+Y%22">Fromage Y</searchLink>; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Ksentini+M%22">Ksentini M</searchLink>; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Labriffe+M%22">Labriffe M</searchLink>; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Monchaud+C%22">Monchaud C</searchLink>; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Codde+C%22">Codde C</searchLink>; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.; Department of Infectious and Tropical Diseases, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Faucher+J-F%22">Faucher J-F</searchLink>; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.; Department of Infectious and Tropical Diseases, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Boutoille+D%22">Boutoille D</searchLink>; Infectious and Tropical Diseases Department, Nantes University, Nantes University Hospital, INSERM, CIC 1413, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Marquet+P%22">Marquet P</searchLink>; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Woillard+J-B%22">Woillard J-B</searchLink>; Department of Pharmacology, Toxicology and Pharmacovigilance, Dupuytren University Hospital (CHU Dupuytren), Limoges, France.; Pharmacology & Transplantation INSERM U1248, University of Limoges, Limoges, France.
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              Text: 2026 Jan 07
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