Can platelet to neutrophil ratio (PNR) serve as a viable alternative tool for monitoring sickle cell disease patients on hydroxyurea in low income countries?

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Title: Can platelet to neutrophil ratio (PNR) serve as a viable alternative tool for monitoring sickle cell disease patients on hydroxyurea in low income countries?
Authors: Chibuife EC; Department of Haematology and Blood Transfusion, Faculty of Basic Clinical Sciences, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria., Chisom Adaobi NE; Department of Paediatrics, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria. ca.nri-ezedi@unizik.edu.ng.; Department of Paediatrics, Nnamdi Azikiwe University, Awka, Anambra, Nigeria. ca.nri-ezedi@unizik.edu.ng., Odini F; Department of Community Medicine, Federal Medical Centre, Umuahia, Abia State, Nigeria., Deepika HD; Division of Hematology, Children's National Hospital and George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Habib NB; Division of Hematology, Children's National Hospital and George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Andrew C; Division of Hematology, Children's National Hospital and George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Source: Annals of hematology [Ann Hematol] 2025 Dec; Vol. 104 (12), pp. 6161-6168. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0584 (Electronic) Linking ISSN: 09395555 NLM ISO Abbreviation: Ann Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0584
DOI:10.1007/s00277-025-06598-2