Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds.

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Title: Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds.
Authors: Bakos E; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary., Tiszlavicz Á; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary., Szegedi V; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary., Douida A; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary., Furdan S; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary., Welter DK; European Molecular Biology Laboratory, Heidelberg, Germany., Landry JM; European Molecular Biology Laboratory, Heidelberg, Germany., Bende B; Hungarian Centre of Excellence for Molecular Medicine Research Group for Translational Medicine Development, Szeged, Hungary., Hutoczki G; Department of Neurosurgery, University of Debrecen Clinical Centre, Debrecen Hungary., Barzo P; Department of Neurosurgery, University of Szeged, Szeged, Hungary., Tamas G; ELKH-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary., Benes V; European Molecular Biology Laboratory, Heidelberg, Germany., Szucs A; Neuronal Cell Biology Research Group, Eötvös Loránd University, Budapest, Hungary., Lamsa K; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary.
Source: PLoS biology [PLoS Biol] 2025 Dec 10; Vol. 23 (12), pp. e3003549. Date of Electronic Publication: 2025 Dec 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1545-7885
DOI:10.1371/journal.pbio.3003549