Loss of Y chromosome in Alzheimer's patients co-occurs with somatic mutations beyond CHIP drivers.

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Title: Loss of Y chromosome in Alzheimer's patients co-occurs with somatic mutations beyond CHIP drivers.
Authors: Rychlicka-Buniowska E; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland edyta.rychlicka-buniowska@gumed.edu.pl., Sarkisyan D; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Horbacz M; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Bruhn-Olszewska B; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Drężek-Chyła K; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Koszyński M; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Davies H; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Juhas U; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.; Department of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, Gdańsk, Poland., Wójcik-Zalewska M; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Klich-Rączka A; Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland., Kilander L; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Ingelsson M; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.; Krembil Brain Institute, University Health Network, Toronto, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Bukowska-Strakova K; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Węglarczyk K; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Siedlar M; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Baran J; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Ryś J; Department of Tumor Pathology, Maria Skłodowska-Curie National Research Institute of Oncology, Kraków, Poland., Piotrowski A; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Filipowicz N; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Dumanski JP; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland jan.dumanski@igp.uu.se.; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Source: Life science alliance [Life Sci Alliance] 2025 Dec 10; Vol. 9 (2). Date of Electronic Publication: 2025 Dec 10 (Print Publication: 2026).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2575-1077
DOI:10.26508/lsa.202503533