Loss of Y chromosome in Alzheimer's patients co-occurs with somatic mutations beyond CHIP drivers.

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Title: Loss of Y chromosome in Alzheimer's patients co-occurs with somatic mutations beyond CHIP drivers.
Authors: Rychlicka-Buniowska E; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland edyta.rychlicka-buniowska@gumed.edu.pl., Sarkisyan D; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Horbacz M; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Bruhn-Olszewska B; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Drężek-Chyła K; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Koszyński M; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Davies H; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Juhas U; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.; Department of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, Gdańsk, Poland., Wójcik-Zalewska M; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Klich-Rączka A; Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland., Kilander L; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Ingelsson M; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.; Krembil Brain Institute, University Health Network, Toronto, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Bukowska-Strakova K; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Węglarczyk K; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Siedlar M; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Baran J; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland., Ryś J; Department of Tumor Pathology, Maria Skłodowska-Curie National Research Institute of Oncology, Kraków, Poland., Piotrowski A; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Filipowicz N; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland., Dumanski JP; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland jan.dumanski@igp.uu.se.; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Source: Life science alliance [Life Sci Alliance] 2025 Dec 10; Vol. 9 (2). Date of Electronic Publication: 2025 Dec 10 (Print Publication: 2026).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE
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  Data: Loss of Y chromosome in Alzheimer's patients co-occurs with somatic mutations beyond CHIP drivers.
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  Data: <searchLink fieldCode="AU" term="%22Rychlicka-Buniowska+E%22">Rychlicka-Buniowska E</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland edyta.rychlicka-buniowska@gumed.edu.pl.<br /><searchLink fieldCode="AU" term="%22Sarkisyan+D%22">Sarkisyan D</searchLink>; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Horbacz+M%22">Horbacz M</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Bruhn-Olszewska+B%22">Bruhn-Olszewska B</searchLink>; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Drężek-Chyła+K%22">Drężek-Chyła K</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Koszyński+M%22">Koszyński M</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Davies+H%22">Davies H</searchLink>; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Juhas+U%22">Juhas U</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.; Department of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Wójcik-Zalewska+M%22">Wójcik-Zalewska M</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Klich-Rączka+A%22">Klich-Rączka A</searchLink>; Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Kilander+L%22">Kilander L</searchLink>; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Ingelsson+M%22">Ingelsson M</searchLink>; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.; Krembil Brain Institute, University Health Network, Toronto, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Bukowska-Strakova+K%22">Bukowska-Strakova K</searchLink>; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Węglarczyk+K%22">Węglarczyk K</searchLink>; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Siedlar+M%22">Siedlar M</searchLink>; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Baran+J%22">Baran J</searchLink>; Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Ryś+J%22">Ryś J</searchLink>; Department of Tumor Pathology, Maria Skłodowska-Curie National Research Institute of Oncology, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Piotrowski+A%22">Piotrowski A</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Filipowicz+N%22">Filipowicz N</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Dumanski+JP%22">Dumanski JP</searchLink>; 3P-Medicine Laboratory, Medical University of Gdańsk, Gdańsk, Poland jan.dumanski@igp.uu.se.; Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
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  Data: <searchLink fieldCode="JN" term="%22101728869%22">Life science alliance</searchLink> [Life Sci Alliance] 2025 Dec 10; Vol. 9 (2). <i>Date of Electronic Publication: </i>2025 Dec 10 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Life+Science+Alliance%2C+LLC%22">Life Science Alliance, LLC </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101728869 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2575-1077 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225751077%22">25751077 </searchLink><i>NLM ISO Abbreviation: </i>Life Sci Alliance <i>Subsets: </i>MEDLINE
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