Structural Mimics of Hydrocarbon Intermediates Reveal Counterclockwise Cyclization Pathways in the Sesquiterpene Synthases TmS and NcECS.
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| Title: | Structural Mimics of Hydrocarbon Intermediates Reveal Counterclockwise Cyclization Pathways in the Sesquiterpene Synthases TmS and NcECS. |
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| Authors: | Groll M; Center for Protein Assemblies, Department Bioscience, School of Natural Sciences, Technical University Munich, Ernst-Otto-Fischer-Straße 8, 85748 Garching, Germany., Li H; Kekulé Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, 53121 Bonn, Germany., Troycke P; Center for Protein Assemblies, Department Bioscience, School of Natural Sciences, Technical University Munich, Ernst-Otto-Fischer-Straße 8, 85748 Garching, Germany., Kaila VRI; Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius väg 16C, 10691 Stockholm, Sweden., Dickschat JS; Kekulé Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, 53121 Bonn, Germany. |
| Source: | Journal of the American Chemical Society [J Am Chem Soc] 2025 Dec 24; Vol. 147 (51), pp. 47742-47750. Date of Electronic Publication: 2025 Dec 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1520-5126 |
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| DOI: | 10.1021/jacs.5c17732 |