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Gene-corrected regulatory T cell therapy for IL2RA deficiency.

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Title: Gene-corrected regulatory T cell therapy for IL2RA deficiency.
Authors: Ha AS; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA., Kalter N; The Institute for Advanced Materials and Nanotechnology, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel., Rosenberg M; The Institute for Advanced Materials and Nanotechnology, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel., Acevedo LA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Liang B; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Liu W; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Paruthiyil S; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Sinha M; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Vu A; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA., Nguyen V; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA., Qi Z; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Krishnappa N; The Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA., Shu J; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Yu J; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Catanzaro J; Department of Immunobiology and Internal Medicine, Yale University, New Haven, CT 06520, USA., Bluestone JA; Sonoma Biotherapeutics, South San Francisco, CA 94080, USA., Tang Q; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA., Urnov FD; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; The Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA., Marson A; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA., Hendel A; The Institute for Advanced Materials and Nanotechnology, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel., Herold KC; Department of Immunobiology and Internal Medicine, Yale University, New Haven, CT 06520, USA., Shy BR; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA. Electronic address: brian.shy@ucsf.edu., Esensten JH; Advanced Biotherapy Center, Sheba Medical Center, Ramat Gan 5266202, Israel. Electronic address: jonathan.esensten@sheba.health.gov.il.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Mar 04; Vol. 34 (3), pp. 1367-1381. Date of Electronic Publication: 2025 Dec 09.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gene-corrected regulatory T cell therapy for IL2RA deficiency.
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  Data: <searchLink fieldCode="AU" term="%22Ha+AS%22">Ha AS</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.<br /><searchLink fieldCode="AU" term="%22Kalter+N%22">Kalter N</searchLink>; The Institute for Advanced Materials and Nanotechnology, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel.<br /><searchLink fieldCode="AU" term="%22Rosenberg+M%22">Rosenberg M</searchLink>; The Institute for Advanced Materials and Nanotechnology, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel.<br /><searchLink fieldCode="AU" term="%22Acevedo+LA%22">Acevedo LA</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Liang+B%22">Liang B</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Paruthiyil+S%22">Paruthiyil S</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Sinha+M%22">Sinha M</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Vu+A%22">Vu A</searchLink>; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+V%22">Nguyen V</searchLink>; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Qi+Z%22">Qi Z</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Krishnappa+N%22">Krishnappa N</searchLink>; The Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA.<br /><searchLink fieldCode="AU" term="%22Shu+J%22">Shu J</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Catanzaro+J%22">Catanzaro J</searchLink>; Department of Immunobiology and Internal Medicine, Yale University, New Haven, CT 06520, USA.<br /><searchLink fieldCode="AU" term="%22Bluestone+JA%22">Bluestone JA</searchLink>; Sonoma Biotherapeutics, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Tang+Q%22">Tang Q</searchLink>; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.<br /><searchLink fieldCode="AU" term="%22Urnov+FD%22">Urnov FD</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; The Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA.<br /><searchLink fieldCode="AU" term="%22Marson+A%22">Marson A</searchLink>; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.<br /><searchLink fieldCode="AU" term="%22Hendel+A%22">Hendel A</searchLink>; The Institute for Advanced Materials and Nanotechnology, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel.<br /><searchLink fieldCode="AU" term="%22Herold+KC%22">Herold KC</searchLink>; Department of Immunobiology and Internal Medicine, Yale University, New Haven, CT 06520, USA.<br /><searchLink fieldCode="AU" term="%22Shy+BR%22">Shy BR</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA. Electronic address: brian.shy@ucsf.edu.<br /><searchLink fieldCode="AU" term="%22Esensten+JH%22">Esensten JH</searchLink>; Advanced Biotherapy Center, Sheba Medical Center, Ramat Gan 5266202, Israel. Electronic address: jonathan.esensten@sheba.health.gov.il.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2026 Mar 04; Vol. 34 (3), pp. 1367-1381. <i>Date of Electronic Publication: </i>2025 Dec 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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