Extracellular matrix deposition drives disease progression and reduces rapamycin response in lymphangioleiomyomatosis.

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Bibliographic Details
Title: Extracellular matrix deposition drives disease progression and reduces rapamycin response in lymphangioleiomyomatosis.
Authors: Clements D; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, UK debbie.clements@nottingham.ac.uk., Babaei-Jadidi R; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, UK., Johnson J; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, UK., Miller S; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, UK., Shah N; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, UK., Sand JMB; Nordic Bioscience A/S, Herlev, Denmark., Leeming DJ; Nordic Bioscience A/S, Herlev, Denmark., Borthwick LA; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Fisher AJ; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne, UK., Dufour A; Department of Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada., Johnson SR; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, UK.; National Centre for Lymphangioleiomyomatosis, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Source: The European respiratory journal [Eur Respir J] 2026 May 21; Vol. 67 (5). Date of Electronic Publication: 2026 May 21 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1399-3003
DOI:10.1183/13993003.00492-2025