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Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets.

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Title: Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets.
Authors: Niederlova V; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.; Department of Cell Biology, Faculty of Science, Charles University, Prague, Czechia., Neuwirth A; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia., Neuman V; Department of Pediatrics, 2nd Faculty of Medicine, Charles University & Motol University Hospital, Prague, Czechia., Michalik J; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia., Charvatova B; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia., Modrak M; Department of Bioinformatics, 2nd Faculty of Medicine, Charles University, Prague, Czechia., Sumnik Z; Department of Pediatrics, 2nd Faculty of Medicine, Charles University & Motol University Hospital, Prague, Czechia., Stepanek O; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia. ondrej.stepanek@img.cas.cz.
Source: Nature communications [Nat Commun] 2025 Dec 11; Vol. 16 (1), pp. 11301. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-66459-4