Synthesis, molecular docking, ADMET studies and biological evaluation of fused pyrazolopyridopyrimidine derivatives as antioxidant and antimicrobial agents.

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Title: Synthesis, molecular docking, ADMET studies and biological evaluation of fused pyrazolopyridopyrimidine derivatives as antioxidant and antimicrobial agents.
Authors: Khalaf HS; Department of Photochemistry, Chemical Industries Research Institute, National Research Centre, Dokki, 12622, Cairo, Egypt. hematsalama2016@gmail.com., El-Sayed AF; Microbial Genetics Department, Biotechnology Research Institute, National Research Centre, Giza, Egypt.; Egypt Center for Research and Regenerative Medicine (ECRRM), Cairo, Egypt., Sediek AA; Chemical Industries Institute, National Research Centre, Dokki, Cairo, 12622, Egypt., Radwan MAA; Applied Organic Chemistry Department, National Research Centre, Dokki, Cairo, 12622, Egypt.
Source: Scientific reports [Sci Rep] 2025 Dec 11; Vol. 15 (1), pp. 43654. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-025-30217-9