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Safety and Efficacy of Micronized Acellular Dermal Matrix Injection for Correction of Moderate to Severe Nasolabial Folds: A Double-Blind, Multicenter, Randomized Controlled, Non-inferior Clinical Trial.

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Title: Safety and Efficacy of Micronized Acellular Dermal Matrix Injection for Correction of Moderate to Severe Nasolabial Folds: A Double-Blind, Multicenter, Randomized Controlled, Non-inferior Clinical Trial.
Authors: Zhang C; Department of Plastic Surgery, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China., Chang X; Department of Plastic Surgery, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China., Chen L; Department of Plastic Surgery, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China., Wang H; Department of Plastic Surgery, West China Hospital of Stomatology, Sichuan University, 14, Section 3, Renmin South Road, Chengdu, 610041, China., Feng G; Department of Plastic Surgery, West China Hospital of Stomatology, Sichuan University, 14, Section 3, Renmin South Road, Chengdu, 610041, China., Zheng W; Department of Plastic Surgery, West China Hospital of Stomatology, Sichuan University, 14, Section 3, Renmin South Road, Chengdu, 610041, China., Li L; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Li, Xicheng District, Beijing, 100050, China., Xu W; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Li, Xicheng District, Beijing, 100050, China., Qi X; Department of Plastic Surgery, Zhujiang Hospital of Southern Medical University, 253 Industrial Avenue, Haizhu District, Guangzhou, 510000, China., Jiang X; Department of Plastic Surgery, Zhujiang Hospital of Southern Medical University, 253 Industrial Avenue, Haizhu District, Guangzhou, 510000, China., Long X; Department of Plastic and Aesthetic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 41, Damucang Hutong, Xicheng District, Beijing, 100032, China., Yu N; Department of Plastic and Aesthetic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 41, Damucang Hutong, Xicheng District, Beijing, 100032, China., Chen L; Beijing Ruijian High-Tech Biological Technology Co., Ltd, Room 202, Building 15, 1, Chaoqian Road, Changping District, Beijing, 102200, China., Long N; Beijing Ruijian High-Tech Biological Technology Co., Ltd, Room 202, Building 15, 1, Chaoqian Road, Changping District, Beijing, 102200, China., Bi H; Department of Plastic Surgery, Peking University Third Hospital, Haidian District, 49 North Garden Road, Beijing, 100191, China. hongsenbi@163.com.
Source: Aesthetic plastic surgery [Aesthetic Plast Surg] 2026 May; Vol. 50 (10), pp. 3710-3719. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Equivalence Trial
Journal Info: Publisher: Springer-Verlag Country of Publication: United States NLM ID: 7701756 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-5241 (Electronic) Linking ISSN: 0364216X NLM ISO Abbreviation: Aesthetic Plast Surg Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-5241
DOI:10.1007/s00266-025-05494-4