Germline Pathogenic Variants Among Women Without a History of Breast Cancer: A Secondary Analysis of the WISDOM Randomized Clinical Trial.
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| Title: | Germline Pathogenic Variants Among Women Without a History of Breast Cancer: A Secondary Analysis of the WISDOM Randomized Clinical Trial. |
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| Authors: | Fergus KB; Cancer Genetics and Prevention Program, University of California, San Francisco., Ross KS; Cancer Genetics and Prevention Program, University of California, San Francisco., Scheuner MT; San Francisco VA Health Care System, San Francisco, California.; Department of Medicine/Hematology-Oncology, University of California, San Francisco.; Department of Pediatrics/Medical Genetics, University of California, San Francisco., Blanco AM; Cancer Genetics and Prevention Program, University of California, San Francisco., Tice JA; Division of General Internal Medicine, Department of Medicine, University of California, San Francisco., Ziv E; Cancer Genetics and Prevention Program, University of California, San Francisco., Shieh Y; Department of Population Health Sciences, Weill Cornell Medicine, New York, New York., van 't Veer L; Department of Laboratory Medicine, University of California, San Francisco., Olopade OI; Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois., Goodman DL; Department of Epidemiology, University of California, Irvine., Tong BS; Cancer Genetics and Prevention Program, University of California, San Francisco., Harvey H; Sanford Health, Sioux Falls, South Dakota., DeRosa D; Moores UCSD Cancer Center, University of California, San Diego, La Jolla., Risty L; Edith Sanford Breast Cancer, Sanford Health, Fargo, North Dakota., Silver E; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles., Kaster A; Edith Sanford Breast Cancer, Sanford Health, Fargo, North Dakota., Fiscalini AS; Department of Surgery, University of California, San Francisco., Blum K; Cancer Genetics and Prevention Program, University of California, San Francisco., Heise R; Department of Population Health Sciences, Weill Cornell Medicine, New York, New York., Sabacan L; Department of Surgery, University of California, San Francisco., Heditsian D; Breast Science Advocacy Core, University of California, San Francisco., Brain S; Breast Science Advocacy Core, University of California, San Francisco., Petruse A; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles., Eklund M; Karolinska Institutet, Stockholm, Sweden., Hiatt RA; Department of Epidemiology & Biostatistics, University of California, San Francisco.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco., Borowsky AD; University of California, Davis, Sacramento., Naeim A; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles., Park HL; Department of Pathology & Laboratory Medicine, University of California, Irvine.; Department of Epidemiology & Biostatistics, University of California, Irvine., LaCroix AZ; Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla., Parker BA; Moores UCSD Cancer Center, University of California, San Diego, La Jolla., Lancaster R; University of Alabama at Birmingham., Esserman J; Diagnostic Center of Miami, Miami, Florida., Wenger N; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles., Arasu V; Division of Research, Kaiser Permanente Division of Research, Pleasanton, California., Anton-Culver H; Department of Epidemiology, University of California, Irvine., Esserman LJ; Cancer Genetics and Prevention Program, University of California, San Francisco., Madlensky L; Moores UCSD Cancer Center, University of California, San Diego, La Jolla.; Division of Genomics and Precision Medicine, Department of Medicine, University of California, San Diego, La Jolla. |
| Source: | JAMA internal medicine [JAMA Intern Med] 2026 Mar 01; Vol. 186 (3), pp. 344-352. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Pragmatic Clinical Trial |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 101589534 Publication Model: Print Cited Medium: Internet ISSN: 2168-6114 (Electronic) Linking ISSN: 21686106 NLM ISO Abbreviation: JAMA Intern Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2168-6114 |
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| DOI: | 10.1001/jamainternmed.2025.7323 |
