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A widespread protein misfolding mechanism is differentially rescued in vitro by chaperones based on gene essentiality.

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Title: A widespread protein misfolding mechanism is differentially rescued in vitro by chaperones based on gene essentiality.
Authors: Sitarik I; Department of Chemistry, Pennsylvania State University, University Park, PA, USA., Vu QV; Department of Chemistry, Pennsylvania State University, University Park, PA, USA., Petucci J; Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA, USA., Frutos P; Department of Biology, Pennsylvania State University, University Park, PA, USA., Song H; Bioinformatics and Genomics Graduate Program, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, USA.; Department of Statistics, Pennsylvania State University, University Park, PA, USA., O'Brien EP; Department of Chemistry, Pennsylvania State University, University Park, PA, USA. epo2@psu.edu.; Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA, USA. epo2@psu.edu.; Bioinformatics and Genomics Graduate Program, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, USA. epo2@psu.edu.
Source: Nature communications [Nat Commun] 2025 Dec 12; Vol. 16 (1), pp. 10870. Date of Electronic Publication: 2025 Dec 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Sitarik+I%22">Sitarik I</searchLink>; Department of Chemistry, Pennsylvania State University, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vu+QV%22">Vu QV</searchLink>; Department of Chemistry, Pennsylvania State University, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Petucci+J%22">Petucci J</searchLink>; Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Frutos+P%22">Frutos P</searchLink>; Department of Biology, Pennsylvania State University, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Song+H%22">Song H</searchLink>; Bioinformatics and Genomics Graduate Program, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, USA.; Department of Statistics, Pennsylvania State University, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22O'Brien+EP%22">O'Brien EP</searchLink>; Department of Chemistry, Pennsylvania State University, University Park, PA, USA. epo2@psu.edu.; Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA, USA. epo2@psu.edu.; Bioinformatics and Genomics Graduate Program, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, USA. epo2@psu.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 12; Vol. 16 (1), pp. 10870. <i>Date of Electronic Publication: </i>2025 Dec 12.
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        Value: 10.1038/s41467-025-66236-3
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