Multi-target design of fused cyclic pyrimidine-2-thione candidates as DNA intercalators and topoisomerase I/II inhibitors.
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| Title: | Multi-target design of fused cyclic pyrimidine-2-thione candidates as DNA intercalators and topoisomerase I/II inhibitors. |
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| Authors: | Khalil MS; Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt., Al-Karmalawy AA; Department of Pharmaceutical Chemistry, College of Pharmacy, The University of Mashreq, Baghdad, Iraq.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, Egypt., Abo Elmaaty A; Medicinal Chemistry Department, Faculty of Pharmacy, Port Said University, Port Said, Egypt.; Medicinal Chemistry Department, Clinical Pharmacy Program, East Port Said National University, Port Said, Egypt., Elsayed GA; Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt., Hassan AMA; Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt. |
| Source: | Future medicinal chemistry [Future Med Chem] 2026 Jan; Vol. 18 (1), pp. 35-48. Date of Electronic Publication: 2025 Dec 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1756-8927 |
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| DOI: | 10.1080/17568919.2025.2602424 |
