The effect of low-dose methotrexate on arterial inflammation in persons living with human immunodeficiency virus: A double-blind randomized placebo-controlled pilot trial.

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Title: The effect of low-dose methotrexate on arterial inflammation in persons living with human immunodeficiency virus: A double-blind randomized placebo-controlled pilot trial.
Authors: Tawakol A; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: atawakol@mgh.harvard.edu., Ribaudo H; Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA., McKhann A; Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Bellinge JW; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Zureigat H; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Fayad ZA; BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lederman MM; Case Western Reserve University School of Medicine, Cleveland, OH, USA., Grinspoon SK; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kuritzkes DR; Division of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Stein JH; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA., Ridker PM; Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Currier JS; David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Hsue P; Department of Medicine, University of California, San Francisco School of Medicine, San Francisco, CA, USA.
Source: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2026 Jun; Vol. 60, pp. 102591. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society of Nuclear Cardiology Country of Publication: United States NLM ID: 9423534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6551 (Electronic) Linking ISSN: 10713581 NLM ISO Abbreviation: J Nucl Cardiol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: The effect of low-dose methotrexate on arterial inflammation in persons living with human immunodeficiency virus: A double-blind randomized placebo-controlled pilot trial.
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  Data: <searchLink fieldCode="AU" term="%22Tawakol+A%22">Tawakol A</searchLink>; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: atawakol@mgh.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Ribaudo+H%22">Ribaudo H</searchLink>; Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McKhann+A%22">McKhann A</searchLink>; Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bellinge+JW%22">Bellinge JW</searchLink>; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zureigat+H%22">Zureigat H</searchLink>; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fayad+ZA%22">Fayad ZA</searchLink>; BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lederman+MM%22">Lederman MM</searchLink>; Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Grinspoon+SK%22">Grinspoon SK</searchLink>; Cardiovascular Imaging Research Center, Departments of Medicine and Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kuritzkes+DR%22">Kuritzkes DR</searchLink>; Division of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Stein+JH%22">Stein JH</searchLink>; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ridker+PM%22">Ridker PM</searchLink>; Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Currier+JS%22">Currier JS</searchLink>; David Geffen School of Medicine, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hsue+P%22">Hsue P</searchLink>; Department of Medicine, University of California, San Francisco School of Medicine, San Francisco, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%229423534%22">Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology</searchLink> [J Nucl Cardiol] 2026 Jun; Vol. 60, pp. 102591. <i>Date of Electronic Publication: </i>2025 Dec 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+of+Nuclear+Cardiology%22">Elsevier Inc. on behalf of American Society of Nuclear Cardiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9423534 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-6551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210713581%22">10713581 </searchLink><i>NLM ISO Abbreviation: </i>J Nucl Cardiol <i>Subsets: </i>MEDLINE; In Process
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              Text: 2026 Jun
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