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Overactive Neuronal eEF2K/eEF2 signaling is associated with cognitive impairment and apathy-like behavior.

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Title: Overactive Neuronal eEF2K/eEF2 signaling is associated with cognitive impairment and apathy-like behavior.
Authors: Jester HM; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Nicol N; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Yang Q; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Zhang Y; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Suhocki A; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Zhou X; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Underwood E; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Pourhadi H; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Cheng D; Department of Cancer Biology, Wake Forest Baptist Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Lee J; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Sun P; Department of Cancer Biology, Wake Forest Baptist Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Furdui CM; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Proud CG; Lifelong Health, South Australian Health and Medical Research Institute, Adelaide, SA, 5001, Australia., Rosenblum K; Sagol Department of Neurobiology, University of Haifa, 3498838, Haifa, Israel., Ma T; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA. tao.ma@wfusm.edu.; Department of Translational Neuroscience, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA. tao.ma@wfusm.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 May; Vol. 31 (5), pp. 2454-2471. Date of Electronic Publication: 2025 Dec 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Overactive Neuronal eEF2K/eEF2 signaling is associated with cognitive impairment and apathy-like behavior.
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  Data: <searchLink fieldCode="AU" term="%22Jester+HM%22">Jester HM</searchLink>; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Nicol+N%22">Nicol N</searchLink>; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Suhocki+A%22">Suhocki A</searchLink>; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+X%22">Zhou X</searchLink>; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Underwood+E%22">Underwood E</searchLink>; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Pourhadi+H%22">Pourhadi H</searchLink>; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+D%22">Cheng D</searchLink>; Department of Cancer Biology, Wake Forest Baptist Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Sun+P%22">Sun P</searchLink>; Department of Cancer Biology, Wake Forest Baptist Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Furdui+CM%22">Furdui CM</searchLink>; Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.<br /><searchLink fieldCode="AU" term="%22Proud+CG%22">Proud CG</searchLink>; Lifelong Health, South Australian Health and Medical Research Institute, Adelaide, SA, 5001, Australia.<br /><searchLink fieldCode="AU" term="%22Rosenblum+K%22">Rosenblum K</searchLink>; Sagol Department of Neurobiology, University of Haifa, 3498838, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Ma+T%22">Ma T</searchLink>; Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA. tao.ma@wfusm.edu.; Department of Translational Neuroscience, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA. tao.ma@wfusm.edu.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 May; Vol. 31 (5), pp. 2454-2471. <i>Date of Electronic Publication: </i>2025 Dec 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
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