A clinical-stage oncology compound selectively targets drug-resistant cancers.

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Title: A clinical-stage oncology compound selectively targets drug-resistant cancers.
Authors: Long K; Stanford University School of Medicine, Stanford, California 94305, USA., Bhattacharjee D; Stanford University School of Medicine, Stanford, California 94305, USA., Newman-Stonebraker SH; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Suhr S; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Mercado BQ; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Scheib E; Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY 10065, USA., Tighe A; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK., Romero L; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Thompson SL; Stanford University School of Medicine, Stanford, California 94305, USA., Sausville EL; Yale University School of Medicine, New Haven, Connecticut 06511, USA., John KM; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Julian L; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Mishra S; Stanford University School of Medicine, Stanford, California 94305, USA., Klingbeil O; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.; Laboratory for Functional Genomics and Gene Regulation, Center for Cancer Biology, VIB, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Gupta P; Stanford University School of Medicine, Stanford, California 94305, USA., Bhatt U; University Hospital Zurich, 8032 Zürich, CH., Gao AC; University of California Davis, Sacramento, California 95817, USA., Ricardo S; Applied Molecular Biosciences Unit (UCIBIO), Toxicologic Pathology Research Laboratory, Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), 4585-116 Gandra, Portugal.; Associate Laboratory i4HB, Institute for Health and Bioeconomy, University Institute of Health Sciences (IUCS), University Polytechnic Higher Education Cooperative (CESPU), CRL, 4585-116 Gandra, Portugal., Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Bornhauser BC; University Hospital Zurich, 8032 Zürich, CH., Corsello SM; Stanford University School of Medicine, Stanford, California 94305, USA., Taylor SS; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK., Chen J; Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY 10065, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA., Holland PL; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Sheltzer JM; Stanford University School of Medicine, Stanford, California 94305, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 03. Date of Electronic Publication: 2026 Feb 03.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.11.26.690878