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When statistics reach their limits: lessons learned from the analysis of the 4D study. Author's reply.

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Title: When statistics reach their limits: lessons learned from the analysis of the 4D study. Author's reply.
Authors: Pereira B; Centre Hospitalier Universitaire (CHU) de Clermont-Ferrand, Délégation à La Recherche Clinique et à L'Innovation (DRCI), Clermont-Ferrand, France., Constantin JM; Département Anesthésie Réanimation, Hôpital La Pitié-Salpêtrière, DMU DREAM, Sorbonne Université, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Godet T; Département Anesthésie Réanimation, Hôpital Estaing, Centre Hospitalier Universitaire (CHU) Clermont-Ferrand, Pôle de Médecine Péri-Opératoire (MPO), Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.; Département de Simulation en Santé, Université Clermont-Auvergne, Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.; Université Clermont-Auvergne, Neuro-Dol, INSERM, Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.
Source: Intensive care medicine [Intensive Care Med] 2026 Jan; Vol. 52 (1), pp. 209-210. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Letter
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1432-1238
DOI:10.1007/s00134-025-08248-7