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When statistics reach their limits: lessons learned from the analysis of the 4D study. Author's reply.

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Title: When statistics reach their limits: lessons learned from the analysis of the 4D study. Author's reply.
Authors: Pereira B; Centre Hospitalier Universitaire (CHU) de Clermont-Ferrand, Délégation à La Recherche Clinique et à L'Innovation (DRCI), Clermont-Ferrand, France., Constantin JM; Département Anesthésie Réanimation, Hôpital La Pitié-Salpêtrière, DMU DREAM, Sorbonne Université, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Godet T; Département Anesthésie Réanimation, Hôpital Estaing, Centre Hospitalier Universitaire (CHU) Clermont-Ferrand, Pôle de Médecine Péri-Opératoire (MPO), Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.; Département de Simulation en Santé, Université Clermont-Auvergne, Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.; Université Clermont-Auvergne, Neuro-Dol, INSERM, Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.
Source: Intensive care medicine [Intensive Care Med] 2026 Jan; Vol. 52 (1), pp. 209-210. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Letter
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Pereira+B%22">Pereira B</searchLink>; Centre Hospitalier Universitaire (CHU) de Clermont-Ferrand, Délégation à La Recherche Clinique et à L'Innovation (DRCI), Clermont-Ferrand, France.<br /><searchLink fieldCode="AU" term="%22Constantin+JM%22">Constantin JM</searchLink>; Département Anesthésie Réanimation, Hôpital La Pitié-Salpêtrière, DMU DREAM, Sorbonne Université, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Godet+T%22">Godet T</searchLink>; Département Anesthésie Réanimation, Hôpital Estaing, Centre Hospitalier Universitaire (CHU) Clermont-Ferrand, Pôle de Médecine Péri-Opératoire (MPO), Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.; Département de Simulation en Santé, Université Clermont-Auvergne, Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.; Université Clermont-Auvergne, Neuro-Dol, INSERM, Clermont-Ferrand, France. tgodet@chu-clermontferrand.fr.
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  Data: <searchLink fieldCode="JN" term="%227704851%22">Intensive care medicine</searchLink> [Intensive Care Med] 2026 Jan; Vol. 52 (1), pp. 209-210. <i>Date of Electronic Publication: </i>2025 Dec 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7704851 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203424642%22">03424642 </searchLink><i>NLM ISO Abbreviation: </i>Intensive Care Med <i>Subsets: </i>MEDLINE; In Process
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        Value: 10.1007/s00134-025-08248-7
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      – Code: eng
        Text: English
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      – TitleFull: When statistics reach their limits: lessons learned from the analysis of the 4D study. Author's reply.
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            NameFull: Pereira B
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              Text: 2026 Jan
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              Y: 2026
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