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High airway thymic stromal lymphopoietin in asthma is associated with type 2 inflammation, mucus plugging, and airway remodeling.

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Title: High airway thymic stromal lymphopoietin in asthma is associated with type 2 inflammation, mucus plugging, and airway remodeling.
Authors: Khanna K; Cardiovascular Research Institute, University of California San Francisco, San Francisco, Calif., Tang M; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California San Francisco, San Francisco, Calif., Jackson ND; Center for Genes, Environment, and Health, National Jewish Health, Denver, Colo., Johansson MW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis., Bleecker ER; Mayo Clinic, Scottsdale, Ariz., Castro M; Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas School of Medicine, The University of Kansas Medical Center, Kansas City, Kan., Comhair SA; Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Denlinger LC; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis., Erzurum SC; Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Hastie AT; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC., Moore W; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC., Israel E; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass., Levy BD; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass., Jarjour NN; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis., Mauger DT; Division of Statistics and Bioinformatics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pa., Phillips BR; Division of Statistics and Bioinformatics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pa., Sumino K; Division of Pulmonary Critical Care Medicine, Washington University, St Louis, Mo., Wenzel SE; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pa., Woodruff PG; Cardiovascular Research Institute, University of California San Francisco, San Francisco, Calif., Seibold MA; Center for Genes, Environment, and Health, National Jewish Health, Denver, Colo; Department of Pediatrics, National Jewish Health, Denver, Colo; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, Colo., Fahy JV; Cardiovascular Research Institute, University of California San Francisco, San Francisco, Calif; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California San Francisco, San Francisco, Calif. Electronic address: john.fahy@ucsf.edu.
Corporate Authors: National Heart, Lung, and Blood Institute Severe Asthma Research Program-3
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 Mar; Vol. 157 (3), pp. 616-626. Date of Electronic Publication: 2025 Dec 13.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High airway thymic stromal lymphopoietin in asthma is associated with type 2 inflammation, mucus plugging, and airway remodeling.
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  Data: <searchLink fieldCode="AU" term="%22Khanna+K%22">Khanna K</searchLink>; Cardiovascular Research Institute, University of California San Francisco, San Francisco, Calif.<br /><searchLink fieldCode="AU" term="%22Tang+M%22">Tang M</searchLink>; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California San Francisco, San Francisco, Calif.<br /><searchLink fieldCode="AU" term="%22Jackson+ND%22">Jackson ND</searchLink>; Center for Genes, Environment, and Health, National Jewish Health, Denver, Colo.<br /><searchLink fieldCode="AU" term="%22Johansson+MW%22">Johansson MW</searchLink>; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.<br /><searchLink fieldCode="AU" term="%22Bleecker+ER%22">Bleecker ER</searchLink>; Mayo Clinic, Scottsdale, Ariz.<br /><searchLink fieldCode="AU" term="%22Castro+M%22">Castro M</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas School of Medicine, The University of Kansas Medical Center, Kansas City, Kan.<br /><searchLink fieldCode="AU" term="%22Comhair+SA%22">Comhair SA</searchLink>; Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Denlinger+LC%22">Denlinger LC</searchLink>; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.<br /><searchLink fieldCode="AU" term="%22Erzurum+SC%22">Erzurum SC</searchLink>; Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Hastie+AT%22">Hastie AT</searchLink>; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC.<br /><searchLink fieldCode="AU" term="%22Moore+W%22">Moore W</searchLink>; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC.<br /><searchLink fieldCode="AU" term="%22Israel+E%22">Israel E</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Levy+BD%22">Levy BD</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Jarjour+NN%22">Jarjour NN</searchLink>; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.<br /><searchLink fieldCode="AU" term="%22Mauger+DT%22">Mauger DT</searchLink>; Division of Statistics and Bioinformatics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pa.<br /><searchLink fieldCode="AU" term="%22Phillips+BR%22">Phillips BR</searchLink>; Division of Statistics and Bioinformatics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pa.<br /><searchLink fieldCode="AU" term="%22Sumino+K%22">Sumino K</searchLink>; Division of Pulmonary Critical Care Medicine, Washington University, St Louis, Mo.<br /><searchLink fieldCode="AU" term="%22Wenzel+SE%22">Wenzel SE</searchLink>; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pa.<br /><searchLink fieldCode="AU" term="%22Woodruff+PG%22">Woodruff PG</searchLink>; Cardiovascular Research Institute, University of California San Francisco, San Francisco, Calif.<br /><searchLink fieldCode="AU" term="%22Seibold+MA%22">Seibold MA</searchLink>; Center for Genes, Environment, and Health, National Jewish Health, Denver, Colo; Department of Pediatrics, National Jewish Health, Denver, Colo; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, Colo.<br /><searchLink fieldCode="AU" term="%22Fahy+JV%22">Fahy JV</searchLink>; Cardiovascular Research Institute, University of California San Francisco, San Francisco, Calif; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California San Francisco, San Francisco, Calif. Electronic address: john.fahy@ucsf.edu.
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  Data: <searchLink fieldCode="JN" term="%221275002%22">The Journal of allergy and clinical immunology</searchLink> [J Allergy Clin Immunol] 2026 Mar; Vol. 157 (3), pp. 616-626. <i>Date of Electronic Publication: </i>2025 Dec 13.
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