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Opportunities for RNA sequencing in physiology: from big data to understanding homeostasis and heterogeneity.

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Title: Opportunities for RNA sequencing in physiology: from big data to understanding homeostasis and heterogeneity.
Authors: Prokop JW; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States.; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States., Bilinovich SM; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Department of Chemistry, Grand Valley State University, Allendale, Michigan, United States., Tokarski E; Center for Epigenetics, Van Andel Institute, Grand Rapids, Michigan, United States., Vishweswaraiah S; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States.; Department of Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States., VanderWeele S; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States., Das AS; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States., Chhetri SB; Center for Computational Biology, Johns Hopkins University, Baltimore, Maryland, United States., Dao A; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States., Arora S; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States., Goodyke A; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States., Buelow KL; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States., Westgate M; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States., VanSickle EA; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States., Edell CJ; Section of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States., Benson LN; Section of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States., Campbell DB; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States., Bupp CP; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Medical Genetics, Corewell Health, Grand Rapids, Michigan, United States., Holsworth A; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Allergy and Immunology, Corewell Health, Grand Rapids, Michigan, United States., Hartog NL; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Allergy and Immunology, Corewell Health, Grand Rapids, Michigan, United States., Krueger JM; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Department of Neurology, Helen DeVos Children's Hospital, Corewell Health, Grand Rapids, Michigan, United States., Cordoba M; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Department of Obstetrics, Gynecology and Women's Health, Corewell Health, Grand Rapids, Michigan, United States., Sims M; Section of Infectious Diseases and International Medicine, Department of Internal Medicine, Beaumont Royal Oak, Royal Oak, Michigan, United States., Tamae Kakazu MA; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Division of Pulmonary and Critical Care, Corewell Health, Grand Rapids, Michigan, United States., Peraino AM; Division of Pulmonary and Critical Care, Corewell Health, Grand Rapids, Michigan, United States., Graham SF; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States.; Department of Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States., Triche T Jr; Center for Epigenetics, Van Andel Institute, Grand Rapids, Michigan, United States., Hussain E; Pediatric Intensive Care Unit, Helen DeVos Children's Hospital, Corewell Health, Grand Rapids, Michigan, United States., Leimanis-Laurens ML; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Pediatric Intensive Care Unit, Helen DeVos Children's Hospital, Corewell Health, Grand Rapids, Michigan, United States., Krawczyk CM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, Michigan, United States., Pollock JS; Section of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States., Rajasekaran S; Corewell Health Research Institute, Corewell Health, Grand Rapids, Michigan, United States.; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.; Pediatric Intensive Care Unit, Helen DeVos Children's Hospital, Corewell Health, Grand Rapids, Michigan, United States.
Source: Function (Oxford, England) [Function (Oxf)] 2026 Feb 01; Vol. 7 (1), pp. e0192025. Date of Electronic Publication: 2025 Dec 08.
Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 101770668 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2633-8823 (Electronic) Linking ISSN: 26338823 NLM ISO Abbreviation: Function (Oxf) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2633-8823
DOI:10.1152/function.019.2025