Cell-specific delivery of GJB2 restores auditory function in mouse models of DFNB1 deafness and mediates appropriate expression in NHP cochlea.

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Title: Cell-specific delivery of GJB2 restores auditory function in mouse models of DFNB1 deafness and mediates appropriate expression in NHP cochlea.
Authors: Ivanchenko MV; Department of Neurobiology, Harvard Medical School, Boston, MA, USA. maryna_ivanchenko@hms.harvard.edu., Booth KTA; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Karavitaki KD; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Antonellis LM; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Nagy MA; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Peters CW; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Price S; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Li Y; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Lytvyn A; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Ward A; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Griffith EC; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Hrvatin S; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Greenberg ME; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Corey DP; Department of Neurobiology, Harvard Medical School, Boston, MA, USA. dcorey@hms.harvard.edu.
Source: Nature communications [Nat Commun] 2025 Dec 16; Vol. 16 (1), pp. 11157. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-66110-2