Implementing Synthetic Multi-Transmembrane Receptor Protein in a Duplex Immunoassay for Assessment of Neutralizing Antibody to a Bispecific Biotherapeutic.
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| Title: | Implementing Synthetic Multi-Transmembrane Receptor Protein in a Duplex Immunoassay for Assessment of Neutralizing Antibody to a Bispecific Biotherapeutic. |
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| Authors: | Wu B; Bioanalytical Discovery and Development Sciences, Johnson & Johnson, 1400 McKean Rd, Spring House, PA, 19477, USA. bwu23@its.jnj.com., Devlin J; Bioanalytical Discovery and Development Sciences, Johnson & Johnson, 1400 McKean Rd, Spring House, PA, 19477, USA., Schnarr M; Bioanalytical Discovery and Development Sciences, Johnson & Johnson, 1400 McKean Rd, Spring House, PA, 19477, USA., Ji Y; Frontage Laboratories, 700 Pennsylvania Dr , Exton, PA, 19341, USA., Zhao B; Frontage Laboratories, 700 Pennsylvania Dr , Exton, PA, 19341, USA., Jiang Y; Bioanalytical Discovery and Development Sciences, Johnson & Johnson, 1400 McKean Rd, Spring House, PA, 19477, USA., Yang TY; Bioanalytical Discovery and Development Sciences, Johnson & Johnson, 1400 McKean Rd, Spring House, PA, 19477, USA. |
| Source: | The AAPS journal [AAPS J] 2025 Dec 17; Vol. 28 (1), pp. 37. Date of Electronic Publication: 2025 Dec 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1550-7416 |
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| DOI: | 10.1208/s12248-025-01188-6 |
