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Unique structural features of the pentameric matrix protein COMP sustain its dynamic regulation of extra- and intracellular activities: A review.

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Title: Unique structural features of the pentameric matrix protein COMP sustain its dynamic regulation of extra- and intracellular activities: A review.
Authors: Boiardi E; COMT - Centre for Molecular and Translational Oncology, Italy; Department of Chemical and Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze, 11/A, 43124, Parma, Italy. Electronic address: erika.boiardi@unipr.it., Demmi S; COMT - Centre for Molecular and Translational Oncology, Italy; Department of Chemical and Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze, 11/A, 43124, Parma, Italy. Electronic address: simona.demmi@unipr.it., Tittaferrante G; COMT - Centre for Molecular and Translational Oncology, Italy; Department of Chemical and Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze, 11/A, 43124, Parma, Italy. Electronic address: graziana.tittaferrante@unipr.it., Lazzaretti M; COMT - Centre for Molecular and Translational Oncology, Italy; Department of Chemical and Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze, 11/A, 43124, Parma, Italy. Electronic address: mirca.lazzaretti@unipr.it., Malpeli G; Department of Life Science, Health, and Health Professions, Link Campus University, Via del Casale di San Pio V, 44, 00165, Roma, Italy. Electronic address: g.malpeli@unilink.it., Brancolini G; Institute of Nanoscience - CNR- NANO, Center S3, Via Giuseppe Campi, 213/A, 41125, Modena, Italy. Electronic address: giorgia.brancolini@cnr.nano.it., Perris R; COMT - Centre for Molecular and Translational Oncology, Italy; Department of Chemical and Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze, 11/A, 43124, Parma, Italy. Electronic address: roberto.perris@unipr.it.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jan; Vol. 338 (Pt 1), pp. 149728. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0003
DOI:10.1016/j.ijbiomac.2025.149728