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Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness.

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Title: Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness.
Authors: Yang S; Department of Neuroscience Yale Medical School, New Haven, CT, USA., Datta D; Department of Neuroscience Yale Medical School, New Haven, CT, USA.; Department of Psychiatry, Yale Medical School, New Haven, CT, USA., Krienen FM; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Woo E; Department of Neuroscience Yale Medical School, New Haven, CT, USA., May A; Department of Neuroscience Yale Medical School, New Haven, CT, USA., Anderson GM; Department of Child Psychiatry, Yale Medical School, New Haven, CT, USA., Galvin VC; Department of Neuroscience Yale Medical School, New Haven, CT, USA., Gonzalez-Burgos G; Departments of Psychiatry and Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA., Lewis DA; Departments of Psychiatry and Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA., Ling E; Department of Genetics, Harvard Medical School, Boston, MA, USA., McCarroll SA; Department of Genetics, Harvard Medical School, Boston, MA, USA., Arnsten AF; Department of Neuroscience Yale Medical School, New Haven, CT, USA., Wang M; Department of Neuroscience Yale Medical School, New Haven, CT, USA. min.wang@yale.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Feb; Vol. 31 (2), pp. 1190-1200.
Publication Type: Journal Article; News
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness.
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  Data: <searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Neuroscience Yale Medical School, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Datta+D%22">Datta D</searchLink>; Department of Neuroscience Yale Medical School, New Haven, CT, USA.; Department of Psychiatry, Yale Medical School, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Krienen+FM%22">Krienen FM</searchLink>; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Woo+E%22">Woo E</searchLink>; Department of Neuroscience Yale Medical School, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22May+A%22">May A</searchLink>; Department of Neuroscience Yale Medical School, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+GM%22">Anderson GM</searchLink>; Department of Child Psychiatry, Yale Medical School, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Galvin+VC%22">Galvin VC</searchLink>; Department of Neuroscience Yale Medical School, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Burgos+G%22">Gonzalez-Burgos G</searchLink>; Departments of Psychiatry and Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+DA%22">Lewis DA</searchLink>; Departments of Psychiatry and Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ling+E%22">Ling E</searchLink>; Department of Genetics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McCarroll+SA%22">McCarroll SA</searchLink>; Department of Genetics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Arnsten+AF%22">Arnsten AF</searchLink>; Department of Neuroscience Yale Medical School, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; Department of Neuroscience Yale Medical School, New Haven, CT, USA. min.wang@yale.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb
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