Exploration of the benefits and resistance mechanisms of immunotherapy based on PD-L1 expression, circulating tumor DNA and T-cell receptor profiles in advanced gastric cancer.

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Title: Exploration of the benefits and resistance mechanisms of immunotherapy based on PD-L1 expression, circulating tumor DNA and T-cell receptor profiles in advanced gastric cancer.
Authors: Gou M; Senior department of oncology, Chinese PLA General hospital, Dongda street 8, Fengtai District, Beijing, 100853, China., Qian N; The Eighth Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China., Zhang Y; Medical Oncology Department, the Second Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China., Yan B; Geneplus-Beijing Institute, Beijing, China.; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China., Wang Z; Senior department of oncology, Chinese PLA General hospital, Dongda street 8, Fengtai District, Beijing, 100853, China., Dai G; Senior department of oncology, Chinese PLA General hospital, Dongda street 8, Fengtai District, Beijing, 100853, China. daigh60@sohu.com.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2025 Dec 19; Vol. 75 (1), pp. 12. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0851
DOI:10.1007/s00262-025-04248-0