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Fructose malabsorption induces dysbiosis and increases anxiety in male human and animal models.

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Title: Fructose malabsorption induces dysbiosis and increases anxiety in male human and animal models.
Authors: Coursan A; Univ. Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, F-33000 Bordeaux, France., Polve D; Univ. Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, F-33000 Bordeaux, France; Université Paris-Saclay, INRAE, AgroParisTech, MICALIS Institute, Jouy-en-Josas, France., Leroi AM; Univ Rouen Normandie, INSERM, ADEN UMR1073, Nutrition, Inflammation and microbiota-gut-brain axis, France; CHU Rouen, CIC-CRB 1404, F-76000 Rouen, France; CHU Rouen, Physiology Department, F-76000 Rouen, France., Monnoye M; Université Paris-Saclay, INRAE, AgroParisTech, MICALIS Institute, Jouy-en-Josas, France., Roussin L; Université Paris-Saclay, INRAE, AgroParisTech, MICALIS Institute, Jouy-en-Josas, France., Benatar C; Université Paris-Saclay, INRAE, AgroParisTech, MICALIS Institute, Jouy-en-Josas, France., Tavolacci MP; Univ Rouen Normandie, INSERM, ADEN UMR1073, Nutrition, Inflammation and microbiota-gut-brain axis, France; CHU Rouen, CIC-CRB 1404, F-76000 Rouen, France., Quillard Muraine M; Univ Rouen Normandie, INSERM, ADEN UMR1073, Nutrition, Inflammation and microbiota-gut-brain axis, France; CHU Rouen, CIC-CRB 1404, F-76000 Rouen, France; CHU Rouen, Department of General Biochemistry, F-76000 Rouen, France., Maccarone M; CHU Rouen, Department of Gastroenterology, F-76000 Rouen, France., Guérin O; CHU Rouen Department of Biostatistics, F-76000 Rouen, France., Houivet E; CHU Rouen Department of Biostatistics, F-76000 Rouen, France., Guérin C; Univ Rouen Normandie, INSERM, ADEN UMR1073, Nutrition, Inflammation and microbiota-gut-brain axis, France., Brunel V; CHU Rouen, Department of General Biochemistry, F-76000 Rouen, France., Bellenger J; LipSTIC LabEx, FCS Bourgogne-Franche Comté, Dijon, France., Pais de Barros JP; LipSTIC LabEx, FCS Bourgogne-Franche Comté, Dijon, France; Plateforme DiviOmics, UMS BioSanD 58, Université de Bourgogne, F-21000 Dijon, France., Gourcerol G; Univ Rouen Normandie, INSERM, ADEN UMR1073, Nutrition, Inflammation and microbiota-gut-brain axis, France; CHU Rouen, CIC-CRB 1404, F-76000 Rouen, France; CHU Rouen, Physiology Department, F-76000 Rouen, France., Naudon L; Université Paris-Saclay, INRAE, AgroParisTech, MICALIS Institute, Jouy-en-Josas, France., Layé S; Univ. Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, F-33000 Bordeaux, France., Madore C; Univ. Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, F-33000 Bordeaux, France., Fioramonti X; Univ. Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, F-33000 Bordeaux, France. Electronic address: xavier.fioramonti@inrae.fr., Melchior C; Univ Rouen Normandie, INSERM, ADEN UMR1073, Nutrition, Inflammation and microbiota-gut-brain axis, France; CHU Rouen, CIC-CRB 1404, F-76000 Rouen, France; CHU Rouen, Department of Gastroenterology, F-76000 Rouen, France., Douard V; Université Paris-Saclay, INRAE, AgroParisTech, MICALIS Institute, Jouy-en-Josas, France. Electronic address: veronique.douard@inrae.fr.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Mar; Vol. 133, pp. 106221. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2139
DOI:10.1016/j.bbi.2025.106221