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Efficacy of tirzepatide versus semaglutide in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial.

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Title: Efficacy of tirzepatide versus semaglutide in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial.
Authors: Neves JS; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal. jsneves@med.up.pt.; Department of Endocrinology, Diabetes and Metabolism, ULS São João, Porto, Portugal. jsneves@med.up.pt., Leite AR; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Endocrinology, Diabetes and Metabolism, ULS São João, Porto, Portugal., Vale C; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Internal Medicine, ULS São João, Porto, Portugal., Marques P; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Internal Medicine, ULS São João, Porto, Portugal., Vasques-Nóvoa F; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Internal Medicine, ULS São João, Porto, Portugal., Leite-Moreira A; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Cardiothoracic Surgery, ULS São João, Porto, Portugal., Ferreira JP; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Université de Lorraine, Inserm, Centre d'Investigations Cliniques - Plurithématique 14-33, Nancy, France.; Inserm U1116, CHRU Nancy, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France.
Source: Diabetologia [Diabetologia] 2026 May; Vol. 69 (5), pp. 1216-1225. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy of tirzepatide versus semaglutide in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial.
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  Data: <searchLink fieldCode="AU" term="%22Neves+JS%22">Neves JS</searchLink>; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal. jsneves@med.up.pt.; Department of Endocrinology, Diabetes and Metabolism, ULS São João, Porto, Portugal. jsneves@med.up.pt.<br /><searchLink fieldCode="AU" term="%22Leite+AR%22">Leite AR</searchLink>; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Endocrinology, Diabetes and Metabolism, ULS São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Vale+C%22">Vale C</searchLink>; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Internal Medicine, ULS São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Marques+P%22">Marques P</searchLink>; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Internal Medicine, ULS São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Vasques-Nóvoa+F%22">Vasques-Nóvoa F</searchLink>; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Internal Medicine, ULS São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Leite-Moreira+A%22">Leite-Moreira A</searchLink>; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Department of Cardiothoracic Surgery, ULS São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Ferreira+JP%22">Ferreira JP</searchLink>; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Université de Lorraine, Inserm, Centre d'Investigations Cliniques - Plurithématique 14-33, Nancy, France.; Inserm U1116, CHRU Nancy, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France.
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  Data: <searchLink fieldCode="JN" term="%220006777%22">Diabetologia</searchLink> [Diabetologia] 2026 May; Vol. 69 (5), pp. 1216-1225. <i>Date of Electronic Publication: </i>2025 Dec 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0006777 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0428 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220012186X%22">0012186X </searchLink><i>NLM ISO Abbreviation: </i>Diabetologia <i>Subsets: </i>MEDLINE
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