Thrombospondin-4 correlates with MRI measures of structural damage and pain sensitisation: a new biomarker in knee osteoarthritis.

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Title: Thrombospondin-4 correlates with MRI measures of structural damage and pain sensitisation: a new biomarker in knee osteoarthritis.
Authors: Howe FA; Neuroscience & Cell Biology Research Institute, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK. Electronic address: howefa@sgul.ac.uk., Koushesh S; Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK. Electronic address: skoushes@sgul.ac.uk., Blundell A; Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK. Electronic address: anna.c.blundell@gmail.com., Law A; Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK; General Internal Medicine, Tunbridge Wells Hospital, Kent TN2 4QJ, UK. Electronic address: amber.law4@nhs.net., Harrison A; Department of Rheumatology, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK. Electronic address: abiola.harrison@nhs.net., Ejindu V; Department of Radiology, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK. Electronic address: Vivian.ejindu@stgeorges.nhs.uk., Taylor-Kuti S; Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK. Electronic address: seyilacine@gmail.com., Niakan A; Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK. Electronic address: m2207412@sgul.ac.uk., Sheppard M; Neuroscience & Cell Biology Research Institute, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK. Electronic address: msheppar@sgul.ac.uk., Ljuhar R; ImageBiopsy Lab, Research & Development, Zehetnergesse 6/2/2, A-1140 Vienna, Austria. Electronic address: r.ljuhar@imagebiopsy.com., Sofat N; Institute for Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, SW17 ORE, UK; Department of Rheumatology, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK. Electronic address: nsofat@citystgeorges.ac.uk.
Source: The Knee [Knee] 2026 Mar; Vol. 59, pp. 104305. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9430798 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5800 (Electronic) Linking ISSN: 09680160 NLM ISO Abbreviation: Knee Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-5800
DOI:10.1016/j.knee.2025.104305