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Berberine inhibits protein citrullination of fibroblast-like synoviocytes by suppressing autophagy via STAT3/PAD4 pathway.

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Title: Berberine inhibits protein citrullination of fibroblast-like synoviocytes by suppressing autophagy via STAT3/PAD4 pathway.
Authors: Song YN; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China; Biochemical Engineering Center of Anhui, Bengbu, Anhui, China. Electronic address: songyining8782@126.com., Zhang F; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: zhangfa20190204@163.com., He Y; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: hy17754839725@163.com., Li YH; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: 17355243387@163.com., Hu FY; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: hfy9017@163.com., Gao Y; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: gaoyi2112@163.com., Zong SY; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: zongshiye@foxmail.com., Wang Y; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China; Biochemical Engineering Center of Anhui, Bengbu, Anhui, China. Electronic address: wangying_0711@126.com., Gao XY; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: 18155762182@163.com., Tang Q; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: 626801229@qq.com., Jiang XM; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: 2675683937@qq.com., Tong FZ; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: 2149856590@qq.com., Yan LP; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China. Electronic address: 2728306092@qq.com., Wei F; School of Pharmacy, Bengbu Medical University, No.2600, Donghai Avenue, Bengbu, Anhui, China; Biochemical Engineering Center of Anhui, Bengbu, Anhui, China; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-related Diseases, China. Electronic address: weifangmailbox@126.com.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2026 Jan; Vol. 150, pp. 157706. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1618-095X
DOI:10.1016/j.phymed.2025.157706