Parietal alpha asymmetry as a diagnostic marker for depression and a predictive biomarker for anhedonia improvement after melatonergic antidepressant treatment.

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Title: Parietal alpha asymmetry as a diagnostic marker for depression and a predictive biomarker for anhedonia improvement after melatonergic antidepressant treatment.
Authors: Lin CE; Department of Psychiatry, Taipei Tzu Chi Hospital, Taipei, Taiwan; Tzu Chi University, Hualien, Taiwan., Chen LF; Graduate Institute of Medical Sciences, National Defense Medical University, Taipei, Taiwan; Taoyuan Psychiatric Center, Ministry of Health and Welfare, Taoyuan, Taiwan., Chang WC; Department of Radiology, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Sack AT; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNs), Brain+Nerve Centre, Maastricht University Medical Centre (MUMC), Maastricht, the Netherlands., Chang CC; Department of Psychiatry, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan. Electronic address: changcc@mail.ndmctsgh.edu.tw., Chang HA; Department of Psychiatry, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan; Non-Invasive Neuromodulation Consortium for Mental Disorders, Society of Psychophysiology, Taipei, Taiwan. Electronic address: chang.ha@mail.ndmctsgh.edu.tw.
Source: Journal of affective disorders [J Affect Disord] 2026 May 01; Vol. 400, pp. 120977. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-2517
DOI:10.1016/j.jad.2025.120977