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Phase 3 randomized trial of postirradiation chemotherapy in patients with newly diagnosed ependymoma: A report from the Children's Oncology Group.

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Title: Phase 3 randomized trial of postirradiation chemotherapy in patients with newly diagnosed ependymoma: A report from the Children's Oncology Group.
Authors: Smith AA; Department of Pediatrics, Cleveland Clinic Children's (A.A.S.)., Onar-Thomas A; Department of Biostatistics, St Jude Children's Research Hospital., Lensing S; Department of Biostatistics, St Jude Children's Research Hospital., Dalton J; Department of Pathology, St Jude Children's Research Hospital., Bennett J; Department of Radiology, St Jude Children's Research Hospital., Tatevossian RG; Department of Pathology, St Jude Children's Research Hospital., Bertrand K; Department of Oncology, St Jude Children's Research Hospital., Lindsay H; Department of Pediatrics, University of Colorado Health Sciences Center., Tabori U; Arthur and Sonia Labatt Brain Tumour Research Centre , Toronto Hospital for Sick Children., Owens-Pickle E; Department of Epidemiology and Biostatistics, University of South Carolina., Blackburn PR; Department of Pathology, St Jude Children's Research Hospital., Handler MH; Department of Neurosurgery, University of Colorado Health Sciences Center., Chambwe N; Department of Pathology, St Jude Children's Research Hospital., El Khoury L; Department of Pathology, St Jude Children's Research Hospital., Lau C; Connecticut Children's Medical Center , The Jackson Laboratory for Genomic Medicine., Kunin-Batson A; Department of Pediatrics, University of Minnesota Medical School., Sands S; Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center., Wu S; Department of Biostatistics, St Jude Children's Research Hospital., Zhou T; Department of Mathematics and Statistics, University of California Long Beach., Chang A; Department of Radiation Medicine, University of California, San Diego., Merchant TE; Department of Radiation Oncology, St Jude Children's Research Hospital., Leary S; Department of Pediatrics, University of Washington, Seattle Children's Hospital., Fouladi M; Department of Pediatrics, Nationwide Children's Hospital., Gajjar A; Department of Oncology, St Jude Children's Research Hospital., Pollack IF; Department of Neurological Surgery, UMPC Children's Hospital of Pittsburg, University of Pittsburg., Foreman NK; Department of Pediatrics, University of Colorado Health Sciences Center., Ellison DW; Department of Pathology, St Jude Children's Research Hospital.
Source: Neuro-oncology [Neuro Oncol] 2026 May 01; Vol. 28 (5), pp. 1286-1297.
Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase 3 randomized trial of postirradiation chemotherapy in patients with newly diagnosed ependymoma: A report from the Children's Oncology Group.
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  Data: <searchLink fieldCode="AU" term="%22Smith+AA%22">Smith AA</searchLink>; Department of Pediatrics, Cleveland Clinic Children's (A.A.S.).<br /><searchLink fieldCode="AU" term="%22Onar-Thomas+A%22">Onar-Thomas A</searchLink>; Department of Biostatistics, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Lensing+S%22">Lensing S</searchLink>; Department of Biostatistics, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Dalton+J%22">Dalton J</searchLink>; Department of Pathology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Bennett+J%22">Bennett J</searchLink>; Department of Radiology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Tatevossian+RG%22">Tatevossian RG</searchLink>; Department of Pathology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Bertrand+K%22">Bertrand K</searchLink>; Department of Oncology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Lindsay+H%22">Lindsay H</searchLink>; Department of Pediatrics, University of Colorado Health Sciences Center.<br /><searchLink fieldCode="AU" term="%22Tabori+U%22">Tabori U</searchLink>; Arthur and Sonia Labatt Brain Tumour Research Centre , Toronto Hospital for Sick Children.<br /><searchLink fieldCode="AU" term="%22Owens-Pickle+E%22">Owens-Pickle E</searchLink>; Department of Epidemiology and Biostatistics, University of South Carolina.<br /><searchLink fieldCode="AU" term="%22Blackburn+PR%22">Blackburn PR</searchLink>; Department of Pathology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Handler+MH%22">Handler MH</searchLink>; Department of Neurosurgery, University of Colorado Health Sciences Center.<br /><searchLink fieldCode="AU" term="%22Chambwe+N%22">Chambwe N</searchLink>; Department of Pathology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22El+Khoury+L%22">El Khoury L</searchLink>; Department of Pathology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Lau+C%22">Lau C</searchLink>; Connecticut Children's Medical Center , The Jackson Laboratory for Genomic Medicine.<br /><searchLink fieldCode="AU" term="%22Kunin-Batson+A%22">Kunin-Batson A</searchLink>; Department of Pediatrics, University of Minnesota Medical School.<br /><searchLink fieldCode="AU" term="%22Sands+S%22">Sands S</searchLink>; Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; Department of Biostatistics, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Zhou+T%22">Zhou T</searchLink>; Department of Mathematics and Statistics, University of California Long Beach.<br /><searchLink fieldCode="AU" term="%22Chang+A%22">Chang A</searchLink>; Department of Radiation Medicine, University of California, San Diego.<br /><searchLink fieldCode="AU" term="%22Merchant+TE%22">Merchant TE</searchLink>; Department of Radiation Oncology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Leary+S%22">Leary S</searchLink>; Department of Pediatrics, University of Washington, Seattle Children's Hospital.<br /><searchLink fieldCode="AU" term="%22Fouladi+M%22">Fouladi M</searchLink>; Department of Pediatrics, Nationwide Children's Hospital.<br /><searchLink fieldCode="AU" term="%22Gajjar+A%22">Gajjar A</searchLink>; Department of Oncology, St Jude Children's Research Hospital.<br /><searchLink fieldCode="AU" term="%22Pollack+IF%22">Pollack IF</searchLink>; Department of Neurological Surgery, UMPC Children's Hospital of Pittsburg, University of Pittsburg.<br /><searchLink fieldCode="AU" term="%22Foreman+NK%22">Foreman NK</searchLink>; Department of Pediatrics, University of Colorado Health Sciences Center.<br /><searchLink fieldCode="AU" term="%22Ellison+DW%22">Ellison DW</searchLink>; Department of Pathology, St Jude Children's Research Hospital.
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  Data: <searchLink fieldCode="JN" term="%22100887420%22">Neuro-oncology</searchLink> [Neuro Oncol] 2026 May 01; Vol. 28 (5), pp. 1286-1297.
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  Data: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100887420 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1523-5866 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215228517%22">15228517 </searchLink><i>NLM ISO Abbreviation: </i>Neuro Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1093/neuonc/noaf285
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              Text: 2026 May 01
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