Validation of a data-driven clustering model for MASLD: Evidence from three large-scale Asian cohorts.

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Title: Validation of a data-driven clustering model for MASLD: Evidence from three large-scale Asian cohorts.
Authors: Zhou XD; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China., Song SJ; Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China., Guo CY; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chen QF; Medical Care Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Institute of Aging, Wenzhou Medical University, Wenzhou, China., Lai-Hung Wong G; Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China., Ye TR; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China., Bee Goh GB; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.; Duke-NUS Medical School, Singapore., Bee YM; Duke-NUS Medical School, Singapore.; Department of Endocrinology, Singapore General Hospital, Singapore., Lian LY; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China., Cheuk-Fung Yip T; Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Che-To Lai J; Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lei SY; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China., Liu WY; Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Fan RC; Department of Cardiovascular Medicine, The Heart Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Hong CL; Department of Cardiovascular Medicine, The Heart Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Targher G; Department of Medicine, University of Verona, Verona, Italy.; Metabolic Diseases Research Unit, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Italy., Byrne CD; Southampton National Institute for Health and Care Research Biomedical Research Centre, University Hospital Southampton, and University of Southampton, Southampton General Hospital, Southampton, UK., Marot G; ULR 2694 METRICS / MODAL, University of Lille, CHU Lille, Inria, Lille, France., Raverdy V; Translational Research for Diabetes UMR 1190, University of Lille, Inserm, Institut Pasteur Lille, CHU Lille, Lille, France., Pattou F; Translational Research for Diabetes UMR 1190, University of Lille, Inserm, Institut Pasteur Lille, CHU Lille, Lille, France., Zheng Lim DY; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.; Duke-NUS Medical School, Singapore.; Data Science and Artificial Intelligence Lab, Singapore General Hospital, Singapore., Wai-Sun Wong V; Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China., Zheng MH; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China.
Source: JHEP reports : innovation in hepatology [JHEP Rep] 2025 Oct 17; Vol. 8 (1), pp. 101645. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: In Process
Database: MEDLINE Ultimate
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ISSN:2589-5559
DOI:10.1016/j.jhepr.2025.101645