Small Extracellular Vesicles Secreted by Cisplatin-Resistant Neuroblastoma Cells Increase Lactate Secretion and Alter Metabolic Pathways in Primary Human Umbilical Vein Endothelial Cells (HUVECs).

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Title: Small Extracellular Vesicles Secreted by Cisplatin-Resistant Neuroblastoma Cells Increase Lactate Secretion and Alter Metabolic Pathways in Primary Human Umbilical Vein Endothelial Cells (HUVECs).
Authors: Frawley T; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland., Ma L; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, China.; College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China., Arifin MZ; Systems Biology Ireland, School of Medicine, University College Dublin, Temple Street, D04 C1P1 Dublin, Ireland., Wu D; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland., Scott A; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland., Cavanagh B; Cellular and Molecular Imaging Core, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland., O'Shea DF; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland., Zhernovkov V; Systems Biology Ireland, School of Medicine, University College Dublin, Temple Street, D04 C1P1 Dublin, Ireland., Liu M; Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, China.; College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China., Monopoli MP; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland., Piskareva O; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland.
Source: Journal of personalized medicine [J Pers Med] 2025 Dec 01; Vol. 15 (12). Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2075-4426
DOI:10.3390/jpm15120584