Generation and ophthalmological characterization of oculocutaneous albinism type 1 pig models by selection-free genome editing.
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| Title: | Generation and ophthalmological characterization of oculocutaneous albinism type 1 pig models by selection-free genome editing. |
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| Authors: | Oh D; Laboratory of Veterinary Embryology and Biotechnology (VETEMBIO), Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.; Institute of Stem Cell and Regenerative Medicine (ISCRM), Chungbuk NationalUniversity, Cheongju, Republic of Korea.; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Seok C; Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea., Park HW; Naason Science, Inc., Cheongju, 28160, Republic of Korea., Park S; Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea., Lee J; Laboratory of Veterinary Embryology and Biotechnology (VETEMBIO), Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.; Institute of Stem Cell and Regenerative Medicine (ISCRM), Chungbuk NationalUniversity, Cheongju, Republic of Korea.; Department of Companion Animal Industry, Semyung University, Jecheon, 27136, Republic of Korea., Choi H; Laboratory of Veterinary Embryology and Biotechnology (VETEMBIO), Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.; Institute of Stem Cell and Regenerative Medicine (ISCRM), Chungbuk NationalUniversity, Cheongju, Republic of Korea.; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Jawad A; Laboratory of Veterinary Embryology and Biotechnology (VETEMBIO), Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.; Institute of Stem Cell and Regenerative Medicine (ISCRM), Chungbuk NationalUniversity, Cheongju, Republic of Korea., Ham J; Laboratory of Veterinary Embryology and Biotechnology (VETEMBIO), Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.; Institute of Stem Cell and Regenerative Medicine (ISCRM), Chungbuk NationalUniversity, Cheongju, Republic of Korea., Jang H; Department of Veterinary Anatomy and Animal Behavior, College of VeterinaryMedicine and BK21 FOUR Program, Chonnam National University, Gwangju, Korea., Lee SC; Cronex Inc., Cheongju, 28174, Korea., Oh BC; Department of Plastic and Reconstructive Surgery, Johns Hopkins UniversitySchool of Medicine, Baltimore, MD, USA., Moon C; Department of Veterinary Anatomy and Animal Behavior, College of VeterinaryMedicine and BK21 FOUR Program, Chonnam National University, Gwangju, Korea., Park KH; Naason Science, Inc., Cheongju, 28160, Republic of Korea. kyungho@naasonscience.com., Hyun SH; Laboratory of Veterinary Embryology and Biotechnology (VETEMBIO), Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea. shhyun@cbu.ac.kr.; Institute of Stem Cell and Regenerative Medicine (ISCRM), Chungbuk NationalUniversity, Cheongju, Republic of Korea. shhyun@cbu.ac.kr.; Graduate School of Veterinary Biosecurity and Protection, Chungbuk NationalUniversity, Cheongju, Republic of Korea. shhyun@cbu.ac.kr., Kim D; Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea. dskim89@skku.edu. |
| Source: | Scientific reports [Sci Rep] 2025 Dec 24; Vol. 15 (1), pp. 44564. Date of Electronic Publication: 2025 Dec 24. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-28385-9 |
