Less Is More: Optimized pharmacotherapy with improved coNtinuity of CarE in hospitaLized oLder peOple (LIMONCELLO): study protocol of a cluster randomized controlled trial.

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Title: Less Is More: Optimized pharmacotherapy with improved coNtinuity of CarE in hospitaLized oLder peOple (LIMONCELLO): study protocol of a cluster randomized controlled trial.
Authors: Cooijmans S; Department of Pharmacy, Pharmacology and Toxicology, Radboud University Medical Center, Mailbox 9101, Geert Grooteplein-Zuid 10, (Route Number 456), 6500 HB, Nijmegen, The Netherlands. sjacky.cooijmans@radboudumc.nl., Engelen EMC; Department of Internal Medicine, Amsterdam University Medical Center - location VUmc, Amsterdam, The Netherlands.; Research and Expertise Centre in Pharmacotherapy Education (RECIPE), Amsterdam, The Netherlands., Wuyts SCM; Research Centre for Digital Medicine, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium., Kramers C; Department of Pharmacy, Pharmacology and Toxicology, Radboud University Medical Center, Mailbox 9101, Geert Grooteplein-Zuid 10, (Route Number 456), 6500 HB, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Clinical Pharmacy, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands., van Agtmael MA; Department of Internal Medicine, Amsterdam University Medical Center - location VUmc, Amsterdam, The Netherlands.; Research and Expertise Centre in Pharmacotherapy Education (RECIPE), Amsterdam, The Netherlands., van den Bemt PMLA; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, The Netherlands., Bouvy ML; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Amouch H; Department of Clinical Pharmacy, Amphia Ziekenhuis, Breda, The Netherlands., Autar RS; Department of Internal Medicine, Amsterdam University Medical Center - location VUmc, Amsterdam, The Netherlands., Benoist GE; Department of Pharmacy, Deventer Ziekenhuis, Deventer, The Netherlands., van Berlo-van de Laar IRF; Department of Pharmacy, Deventer Ziekenhuis, Deventer, The Netherlands., Derijks-Engwegen JYMN; Department of Pharmacy, Pharmacology and Toxicology, Radboud University Medical Center, Mailbox 9101, Geert Grooteplein-Zuid 10, (Route Number 456), 6500 HB, Nijmegen, The Netherlands., van den Elsen G; Department of Clinical Geriatrics, Ziekenhuisgroep Twente, Almelo, The Netherlands., Engelaer FM; Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands., Gombert-Handoko KB; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands., Jansen DRM; Department of Geriatrics, Radboud University Medical Center, Nijmegen, The Netherlands., Kerskes MHM; Department of Clinical Pharmacy, Catharina Ziekenhuis, Eindhoven, The Netherlands., Kruik-Kollöffel WJ; Department of Clinical Pharmacy, Ziekenhuisgroep Twente, Almelo and Hengelo, The Netherlands., Kuijvenhoven MA; Pharmacy & Clinical Pharmacology, Amsterdam University Medical Center, Amsterdam, The Netherlands., van der Kuy HM; Department of Hospital Pharmacy, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Labots G; Department of Internal Medicine, HagaZiekenhuis, Den Haag, The Netherlands., van Poelgeest EP; Department of Internal Medicine, Geriatrics, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Sablerolles R; Department of Hospital Pharmacy, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Sallevelt BTG; Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van Stiphout F; Department of Geriatric Medicine, Meander Medical Center, Amersfoort, The Netherlands., Storm BN; Department of Hospital Pharmacy, HagaZiekenhuis, Den Haag, The Netherlands., Taks M; Department of Clinical Pharmacy, Amphia Ziekenhuis, Breda, The Netherlands., Teeuwisse PJI; Department of Pharmacy and Clinical Pharmacology, Amsterdam University Medical Center Location AMC, Amsterdam, The Netherlands., Uiterwijk J; Department of Clinical Pharmacy, Catharina Ziekenhuis, Eindhoven, The Netherlands., Vondeling A; Department of Clinical Geriatrics, Diakonessenhuis, Utrecht, Zeist and Doorn, The Netherlands., de Vries M; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., Wesselink E; Department of Clinical Pharmacy, Zaans Medical Center, Zaandam, The Netherlands., Wiggers NML; Department of Clinical Pharmacy, Zaans Medical Center, Zaandam, The Netherlands., de Wit HAJM; Department of Clinical Pharmacy, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands., Schers HJ; Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, The Netherlands., Adang EMM; Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands., van Wely M; Center for Reproductive Medicine, Amsterdam Reproduction & Development Research Institute, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., van Herwaarden N; Department of Pharmacy, Pharmacology and Toxicology, Radboud University Medical Center, Mailbox 9101, Geert Grooteplein-Zuid 10, (Route Number 456), 6500 HB, Nijmegen, The Netherlands.; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands., Knol W; Department of Geriatric Medicine and Expertise Centre Pharmacotherapy in Older People, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Source: BMC geriatrics [BMC Geriatr] 2025 Dec 24; Vol. 25 (1), pp. 1034. Date of Electronic Publication: 2025 Dec 24.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968548 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2318 (Electronic) Linking ISSN: 14712318 NLM ISO Abbreviation: BMC Geriatr Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1471-2318
DOI:10.1186/s12877-025-06533-0