The role of MICOS in modulating mitochondrial dynamics and structural changes in vulnerable regions of Alzheimer's Disease.

Saved in:
Bibliographic Details
Title: The role of MICOS in modulating mitochondrial dynamics and structural changes in vulnerable regions of Alzheimer's Disease.
Authors: Shao B; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Kula B; Del Monte Institute for Neuroscience, Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA., Le H; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; Department of Integrative Genomics and Epidemiology, Meharry Medical College, Nashville, TN, USA.; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA., Venkhatesh P; Department of Biology, Indian Institute of Science Education and Research (IISER) Tirupati, AP, 517619, India.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA., Katti P; Department of Biology, Indian Institute of Science Education and Research (IISER) Tirupati, AP, 517619, India.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA., Marshall AG; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA.; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA., Chittaranjan S; Del Monte Institute for Neuroscience, Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA., Thapilyal S; Department of Biology, Indian Institute of Science Education and Research (IISER) Tirupati, AP, 517619, India.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA., Namdar HK; Department of Biology, Indian Institute of Science Education and Research (IISER) Tirupati, AP, 517619, India.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA., Nivedya C; Department of Biology, Indian Institute of Science Education and Research (IISER) Tirupati, AP, 517619, India.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA., Roszczyk A; Del Monte Institute for Neuroscience, Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA., Mobley H; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Killion M; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., St John E; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Martin P; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA., Rodrigiuez B; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA.; Department of Integrative Genomics and Epidemiology, Meharry Medical College, Nashville, TN, USA., Hamilton M; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA., Bell L; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA., Wyckoff SM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Moran LA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Philips M; Department of Integrative Biology, Oregon State University, Corvallis, OR, USA., Hubert D; Department of Integrative Biology, Oregon State University, Corvallis, OR, USA., Tomeau B; Department of Integrative Genomics and Epidemiology, Meharry Medical College, Nashville, TN, USA., Afolabi JM; Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA., Kirabo A; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Institute for Infection, Immunology and Inflammation (VI4), Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN, USA., Blanco I; Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA., Reasonover S; Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA., Drake LE; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Lippmann ES; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Evans C; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA.; Howard Hughes Medical Institute, Duke University School of Medicine, Durham, NC, USA., Santisteban MM; Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA., Cheairs TG; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA., Mesenga S; Departments of Physiological Sciences, Pathology and Microbiology, HAND Research Group, School of Medicine and Health Sciences, Livingstone, Zambia.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN, USA., Wanjalla C; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA., Gaddy J; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA., McMillan R; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA., Hernandez Perez CP; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Paing HH; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Schafer JC; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Mobley B; Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA., Berry J; Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA., Crabtree A; Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, USA.; Frist Center for Autism & Innovation, Vanderbilt University, Nashville, TN, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Kovtun O; Department of Chemistry, Vanderbilt University, Nashville, TN, USA., Goodwin S; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA., Garza Lopez E; Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA.; Del Monte Institute for Neuroscience, Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.; Department of Biology, Indian Institute of Science Education and Research (IISER) Tirupati, AP, 517619, India., Dash C; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA., Dai DF; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Miller-Fleming TW; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Hinton A Jr; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; Frist Center for Autism & Innovation, Vanderbilt University, Nashville, TN, USA.; Department of Medicine, Division of Cardiology, Vanderbilt University Medical Center, Nashville, TN, USA.; The Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN, USA.; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN, USA.; Department of Biochemistry, Cancer Biology, Pharmacology and Neuroscience, Meharry Medical College, Nashville, TN, USA.; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA., Smith NA; Del Monte Institute for Neuroscience, Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 16. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2025.12.13.693635