Philadelphia chromosome-positive acute lymphoblastic leukaemia in children and adolescents: A changing treatment landscape and a methodological challenge.

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Bibliographic Details
Title: Philadelphia chromosome-positive acute lymphoblastic leukaemia in children and adolescents: A changing treatment landscape and a methodological challenge.
Authors: Balduzzi A; Department of Pediatrics, Pediatric Hematology-Oncology Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy., Valsecchi MG; School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Tran TH; Division of Pediatric Hematology-Oncology, Charles-Bruneau Cancer Center, Centre Hospitalier Universitaire Sainte-Justine, Montréal, Quebec, Canada.; Department of Pediatrics, Faculty of Medicine, University of Montréal, Montréal, Quebec, Canada., Zuna J; CLIP (Childhood Leukaemia Investigation Prague), Prague, Czech Republic.; Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; University Hospital Motol, Prague, Czech Republic., Leoni V; Department of Pediatrics, Pediatric Hematology-Oncology Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Cario G; Department of Pediatrics I, Pediatric Hematology and Oncology, ALL-BFM Study Group, University Medical Center Schleswig-Holstein, Kiel, Germany., Fazio G; School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Gandemer V; Department of Pediatric Hematology and Oncology, CHU Hôpital Sud, Rennes, France., Tasian SK; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pediatrics and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., van der Sluis IM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Peccatori N; Department of Pediatrics, Pediatric Hematology-Oncology Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy., Parasole R; Department of Oncology, Hematology and Cellular Therapy, Santobono-Pausilipon Children's Hospital, Naples, Italy., Monterisi S; Clinical Trials and Phase I Unit, Pediatric Hematology-Oncology Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Loh ML; Seattle Children's Hospital, Seattle, Washington, USA.; Ben Towne Center for Childhood Cancer and Blood Disorders Research and Department of Pediatrics, Fred Hutchinson Cancer Center, University of Washington, Seattle, Washington, USA., Devidas M; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Hunger SP; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Kairalla JA; Department of Biostatistics, Colleges of Medicine and Public Health & Health Professions, University of Florida, Gainesville, Florida, USA., De Lorenzo P; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Silverman LB; Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Columbia University Irving Medical Center, New York, New York, USA., Biondi A; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Source: British journal of haematology [Br J Haematol] 2026 Mar; Vol. 208 (3), pp. 1127-1132. Date of Electronic Publication: 2025 Dec 25.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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