Identification of Novel Susceptibility Genes for Early-Onset Colorectal Cancer Through Germline Rare Variant Burden Testing.
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| Title: | Identification of Novel Susceptibility Genes for Early-Onset Colorectal Cancer Through Germline Rare Variant Burden Testing. |
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| Authors: | Song R; Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA., Mikaeel RR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., He Z; Department of Biostatistics, University of Florida, Gainesville, FL 32611, USA., Horsnell M; Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia., Uylaki W; Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia., Meng W; Department of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL 32611, USA., Poplawski NK; Adult Genetics Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia., Wollnik B; Institute of Human Genetics, University Medical Center Göttingen, 37075 Göttingen, Germany., Li Y; Institute of Human Genetics, University Medical Center Göttingen, 37075 Göttingen, Germany., Feng J; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5001, Australia.; Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, SA 5000, Australia., Scott HS; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5001, Australia.; Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, SA 5000, Australia.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia., Shen Y; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA., Wang C; Department of Biostatistics, Columbia University Irving Medical Center, New York, NY 10032, USA., Yin R; Department of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL 32611, USA., Ding Y; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development, University of Florida, Gainesville, FL 32611, USA., Llor X; Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06520, USA., Chung WK; Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Smith E; Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia., Price TJ; Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia., Young JP; Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia., Fan X; Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.; University of Florida Health Cancer Center, Gainesville, FL 32610, USA. |
| Source: | Cancers [Cancers (Basel)] 2025 Dec 09; Vol. 17 (24). Date of Electronic Publication: 2025 Dec 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2072-6694 |
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| DOI: | 10.3390/cancers17243931 |
