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Multiscale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts.

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Bibliographic Details
Title: Multiscale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts.
Authors: Molina-Riquelme I; Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago de Chile 8331150, Chile., Barrientos G; Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago de Chile 8331150, Chile., Breitsprecher L; Center of Cellular Nanoanalytics, Integrated Bioimaging Facility, University of Osnabrück, Osnabrück, Lower Saxony 49076, Germany., Gómez W; Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago de Chile 8331150, Chile., Díaz-Castro F; Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago de Chile 8331150, Chile., Morris S; Institute of Integrative Cell Biology and Physiology, Faculty of Biology, University of Muenster, Muenster, North-Rhine-Westphalia 48149, Germany., Almarza G; Laboratorio de Fisiología y Bioenergética Celular, Departamento de Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago de Chile 7820436, Chile., Del Campo A; Laboratorio de Fisiología y Bioenergética Celular, Departamento de Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago de Chile 7820436, Chile., Garrido-Olivares L; Laboratorio de Fisiología y Bioenergética Celular, Departamento de Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago de Chile 7820436, Chile., Verdejo HE; Facultad de Medicina, División de Cirugía, Pontificia Universidad Católica de Chile, Santiago de Chile 8331150, Chile., Psathaki OE; Center of Cellular Nanoanalytics, Integrated Bioimaging Facility, University of Osnabrück, Osnabrück, Lower Saxony 49076, Germany., Busch KB; Institute of Integrative Cell Biology and Physiology, Faculty of Biology, University of Muenster, Muenster, North-Rhine-Westphalia 48149, Germany., Eisner V; Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago de Chile 8331150, Chile.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jan 06; Vol. 123 (1), pp. e2508911123. Date of Electronic Publication: 2025 Dec 30.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2508911123