Early start of opicapone in Parkinson's disease: evidence from a pooled analysis of phase 3 trials for sustained benefit in patients with recent onset of motor fluctuations.
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| Title: | Early start of opicapone in Parkinson's disease: evidence from a pooled analysis of phase 3 trials for sustained benefit in patients with recent onset of motor fluctuations. |
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| Authors: | Ferreira JJ; Laboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina, Universidade Lisboa, Lisbon, Portugal.; CNS - Campus Neurológico, Torres Vedras, Portugal., Stocchi F; Institute for Research and Medical Care IRCCS San Raffaele, Roma, Italy.; San Raffaele University, Rome, Italy., Antonini A; Neurodegenerative Disease Unit, Centre for Rare Neurological Diseases (ERN-RND), Department of Neuroscience, University of Padova, Padova, Italy.; IRCCS San Camillo, Venice, Italy., Rascol O; NS-Park Network, Toulouse, France.; Department of Clinical Pharmacology and Neurosciences, Toulouse Parkinson Expert Centre, Toulouse NeuroToul Center of Excellence in Neurodegeneration (COEN), French NS-Park/F-CRIN Network, University of Toulouse 3, CHU of Toulouse, INSERM, Toulouse, France., Ebersbach G; Movement Disorders Hospital, Beelitz-Heilstätten, Beelitz, Germany., Kulisevsky J; Movement Disorders Unit, Neurology Department, Sant Pau Hospital, Barcelona, Spain.; Biomedical Research Institute (IIB-Sant Pau), Barcelona, Catalunya, Spain.; Center for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain., Fonseca MM; BIAL - R&D Investments, S.A., Porto, Portugal., Ramos D; BIAL - Portela & Ca, S.A., Coronado, Portugal., Rocha JF; BIAL - Portela & Ca, S.A., Coronado, Portugal., Brigas HC; BIAL - Portela & Ca, S.A., Coronado, Portugal., Holenz J; BIAL - Portela & Ca, S.A., Coronado, Portugal., Poewe W; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria. |
| Source: | Frontiers in neurology [Front Neurol] 2025 Dec 15; Vol. 16, pp. 1715748. Date of Electronic Publication: 2025 Dec 15 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2295 (Print) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-2295 |
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| DOI: | 10.3389/fneur.2025.1715748 |
