JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease.

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Title: JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease.
Authors: Zhao Y; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States.; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States., Duan J; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States.; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States., Seah H; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States.; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States., van de Leemput J; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States.; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States., Han Z; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States.; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, United States.
Source: ELife [Elife] 2025 Dec 31; Vol. 13. Date of Electronic Publication: 2025 Dec 31.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2050-084X
DOI:10.7554/eLife.96987