View in EDS

Molecular and phenotypic blueprint of human hematopoiesis links proliferation stress to stem cell aging.

Saved in:
Bibliographic Details
Title: Molecular and phenotypic blueprint of human hematopoiesis links proliferation stress to stem cell aging.
Authors: Lettera E; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy., Basso-Ricci L; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Carsana E; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Giannetti K; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Tavella T; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Seffin L; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy., Farina G; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Gualandi N; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Quaranta P; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy., Lo Furno E; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Pacini G; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Della Volpe L; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Kaufmann KB; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada., Garcia-Prat L; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada., Hernandez RJ; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Murison A; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada., Aguilar-Navarro AG; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.; Unidad de Investigación Médica en Enfermedades Oncológicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social , Mexico City, Mexico., Beretta S; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Conti A; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Flores-Figueroa E; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.; Unidad de Investigación Médica en Enfermedades Oncológicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social , Mexico City, Mexico., Ometti M; Department of Orthopedic Surgery and Traumatology, IRCCS Ospedale San Raffaele, Milan, Italy., Merelli I; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Aiuti A; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy.; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute , Milan, Italy., Xie SZ; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Scala S; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy., Di Micco R; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; University School of Advanced Studies IUSS , Pavia, Italy.
Source: The Journal of experimental medicine [J Exp Med] 2026 Feb 02; Vol. 223 (2). Date of Electronic Publication: 2025 Dec 30.
Publication Type: Journal Article
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41474970
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Molecular and phenotypic blueprint of human hematopoiesis links proliferation stress to stem cell aging.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Lettera+E%22">Lettera E</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Basso-Ricci+L%22">Basso-Ricci L</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Carsana+E%22">Carsana E</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Giannetti+K%22">Giannetti K</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tavella+T%22">Tavella T</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Seffin+L%22">Seffin L</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Farina+G%22">Farina G</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gualandi+N%22">Gualandi N</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Quaranta+P%22">Quaranta P</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lo+Furno+E%22">Lo Furno E</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pacini+G%22">Pacini G</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Della+Volpe+L%22">Della Volpe L</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Kaufmann+KB%22">Kaufmann KB</searchLink>; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Garcia-Prat+L%22">Garcia-Prat L</searchLink>; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Hernandez+RJ%22">Hernandez RJ</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Murison+A%22">Murison A</searchLink>; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Aguilar-Navarro+AG%22">Aguilar-Navarro AG</searchLink>; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.; Unidad de Investigación Médica en Enfermedades Oncológicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social , Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Beretta+S%22">Beretta S</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Conti+A%22">Conti A</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Flores-Figueroa+E%22">Flores-Figueroa E</searchLink>; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.; Unidad de Investigación Médica en Enfermedades Oncológicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social , Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Ometti+M%22">Ometti M</searchLink>; Department of Orthopedic Surgery and Traumatology, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Merelli+I%22">Merelli I</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Aiuti+A%22">Aiuti A</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; Università Vita-Salute San Raffaele , Milan, Italy.; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Xie+SZ%22">Xie SZ</searchLink>; University Health Network, Princess Margaret Cancer Centre , Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Scala+S%22">Scala S</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Micco+R%22">Di Micco R</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS Ospedale San Raffaele , Milan, Italy.; University School of Advanced Studies IUSS , Pavia, Italy.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%222985109R%22">The Journal of experimental medicine</searchLink> [J Exp Med] 2026 Feb 02; Vol. 223 (2). <i>Date of Electronic Publication: </i>2025 Dec 30.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Rockefeller+University+Press%22">Rockefeller University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985109R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1540-9538 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221007%22">00221007 </searchLink><i>NLM ISO Abbreviation: </i>J Exp Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41474970
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1084/jem.20251805
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Molecular and phenotypic blueprint of human hematopoiesis links proliferation stress to stem cell aging.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Lettera E
      – PersonEntity:
          Name:
            NameFull: Basso-Ricci L
      – PersonEntity:
          Name:
            NameFull: Carsana E
      – PersonEntity:
          Name:
            NameFull: Giannetti K
      – PersonEntity:
          Name:
            NameFull: Tavella T
      – PersonEntity:
          Name:
            NameFull: Seffin L
      – PersonEntity:
          Name:
            NameFull: Farina G
      – PersonEntity:
          Name:
            NameFull: Gualandi N
      – PersonEntity:
          Name:
            NameFull: Quaranta P
      – PersonEntity:
          Name:
            NameFull: Lo Furno E
      – PersonEntity:
          Name:
            NameFull: Pacini G
      – PersonEntity:
          Name:
            NameFull: Della Volpe L
      – PersonEntity:
          Name:
            NameFull: Kaufmann KB
      – PersonEntity:
          Name:
            NameFull: Garcia-Prat L
      – PersonEntity:
          Name:
            NameFull: Hernandez RJ
      – PersonEntity:
          Name:
            NameFull: Murison A
      – PersonEntity:
          Name:
            NameFull: Aguilar-Navarro AG
      – PersonEntity:
          Name:
            NameFull: Beretta S
      – PersonEntity:
          Name:
            NameFull: Conti A
      – PersonEntity:
          Name:
            NameFull: Flores-Figueroa E
      – PersonEntity:
          Name:
            NameFull: Ometti M
      – PersonEntity:
          Name:
            NameFull: Merelli I
      – PersonEntity:
          Name:
            NameFull: Aiuti A
      – PersonEntity:
          Name:
            NameFull: Xie SZ
      – PersonEntity:
          Name:
            NameFull: Scala S
      – PersonEntity:
          Name:
            NameFull: Di Micco R
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 02
              Text: 2026 Feb 02
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1540-9538
          Numbering:
            – Type: volume
              Value: 223
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: The Journal of experimental medicine
              Type: main
ResultId 1