Multicentre preclinical profiling of apramycin for the treatment of nontuberculous mycobacteria.

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Title: Multicentre preclinical profiling of apramycin for the treatment of nontuberculous mycobacteria.
Authors: Nguyen MH; Division of Mycobacterial and Respiratory Infections, Department of Medicine, National Jewish Health, Denver, CO, USA; Division of Infectious Diseases, Department of Internal Medicine, University of California, Davis Health, Sacramento, CA, USA. Electronic address: mvunguyen@health.ucdavis.edu., Plattner M; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Verma D; Colorado State University, Fort Collins, CO, USA., Krishnamurthy RV; Foundation for Neglected Disease Research, Bengaluru, India., Xie M; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Calado Nogueira de Moura V; Division of Mycobacterial and Respiratory Infections, Department of Medicine, National Jewish Health, Denver, CO, USA., Haldimann K; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Lang R; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Becker K; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Kaur P; Foundation for Neglected Disease Research, Bengaluru, India., Shandil RK; Foundation for Neglected Disease Research, Bengaluru, India., Singh M; Foundation for Neglected Disease Research, Bengaluru, India., Bulman ZP; Department of Pharmacy Practice, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, USA., Dick T; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Narayanan S; Foundation for Neglected Disease Research, Bengaluru, India., Schulthess B; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland; National Reference Center for Mycobacteria, Zurich, Switzerland., Mitarai S; Research Institute of Tuberculosis, Kiyose-shi, Tokyo, Japan., Daley CL; Division of Mycobacterial and Respiratory Infections, Department of Medicine, National Jewish Health, Denver, CO, USA; Department of Medicine, University of Colorado, Aurora, CO, USA., Hobbie SN; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland; Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland. Electronic address: sven.hobbie@usb.ch.
Source: EBioMedicine [EBioMedicine] 2026 Jan; Vol. 123, pp. 106103. Date of Electronic Publication: 2025 Dec 31.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2352-3964
DOI:10.1016/j.ebiom.2025.106103