Disruption of protein-protein interaction hotspots in the C-terminal domain of MLH1 confers mismatch repair deficiency.
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| Title: | Disruption of protein-protein interaction hotspots in the C-terminal domain of MLH1 confers mismatch repair deficiency. |
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| Authors: | Fishwick KM; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland., Gomez Vieito D; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland., Greco G; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland., Collotta G; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland., Gatti M; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland., Kulik AA; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland., Guérois R; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198 Gif-sur-Yvette, France., Corbeski I; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Phadte AS; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, United States., Senoussi I; Faculty of Biomedical Sciences, Institute for Research in Biomedicine, Università della Svizzera Italiana (USI), CH-6500 Bellinzona, Switzerland., Cejka P; Faculty of Biomedical Sciences, Institute for Research in Biomedicine, Università della Svizzera Italiana (USI), CH-6500 Bellinzona, Switzerland., Pluciennik A; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, United States., Porro A; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland., Sartori AA; Institute of Molecular Cancer Research, University of Zurich, Strickhofstrasse 40a, CH-8057 Zurich, Switzerland. |
| Source: | NAR cancer [NAR Cancer] 2025 Dec 31; Vol. 7 (4), pp. zcaf055. Date of Electronic Publication: 2025 Dec 31 (Print Publication: 2025). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2632-8674 |
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| DOI: | 10.1093/narcan/zcaf055 |
