Tight junction-high and CDH17-positive cell population is the source of colorectal cancer liver metastases.
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| Title: | Tight junction-high and CDH17-positive cell population is the source of colorectal cancer liver metastases. |
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| Authors: | Alvarez-Villanueva D; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain.; Chemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Spain., Maqueda M; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain., Harti D; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain., Canton E; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain.; Josep Carreras Leukemia Research Institute, Badalona, Spain., Andrades E; Dermatology Department, Hospital del Mar, Barcelona, Spain., Bertran J; Faculty of Sciences, Technology and Engineering, Universitat de Vic - Universitat Central de Catalunya, Barcelona, Spain., Martínez-Iniesta M; Chemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Spain., Solé L; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain.; Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain., García-Hernández V; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain., Montoto Á; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain., Lobo-Jarne T; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain., Alonso-Marañón J; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain., Herrero-Molinero P; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain., Larrubia-Loring M; Pathology Department, Hospital del Mar, Barcelona, Spain., Tramuns A; Pathology Department, Hospital del Mar, Barcelona, Spain., Wynne K; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Dublin, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland., Bera I; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland., Matallanas D; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland., Villanueva A; Chemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Spain., Bigas A; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain.; Josep Carreras Leukemia Research Institute, Badalona, Spain.; Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain., Iglesias M; Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain.; Pathology Department, Hospital del Mar, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Espinosa L; Cancer Research Program, Hospital del Mar Research Institute, Barcelona, Spain. lespinosa@researchmar.net.; Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain. lespinosa@researchmar.net. |
| Source: | Nature communications [Nat Commun] 2026 Jan 03; Vol. 17 (1), pp. 1425. Date of Electronic Publication: 2026 Jan 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-68169-3 |
