Afatinib exerts an inhibitory effect on T cell-mediated cytotoxicity.

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Title: Afatinib exerts an inhibitory effect on T cell-mediated cytotoxicity.
Authors: Yokomura M; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-Ku, Tokyo, 135-8550, Japan.; Department of Head and Neck Surgery, Institute of Science Tokyo, Tokyo, Japan., Nagano S; Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan., Kawamoto H; Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan., Hirohashi Y; Department of Pathology, School of Medicine, Sapporo Medical University, Sapporo, Japan., Torigoe T; Department of Pathology, School of Medicine, Sapporo Medical University, Sapporo, Japan., Asakage T; Department of Head and Neck Surgery, Institute of Science Tokyo, Tokyo, Japan., Katayama R; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-Ku, Tokyo, 135-8550, Japan. ryohei.katayama@jfcr.or.jp.; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan. ryohei.katayama@jfcr.or.jp.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Jan 03; Vol. 75 (1), pp. 33. Date of Electronic Publication: 2026 Jan 03.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0851
DOI:10.1007/s00262-025-04279-7