A Phase 1, Open-Label, Single Ascending Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ES-481 After Oral Administration in Healthy Volunteers.
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| Title: | A Phase 1, Open-Label, Single Ascending Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ES-481 After Oral Administration in Healthy Volunteers. |
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| Authors: | Niecestro R; ES-Therapeutics, New York, NY, USA. rniecestro@estherapeutics.com.; ES Therapeutics, Inc., 13053 Big Bear Bluff, Boynton Beach, FL, 33473, USA. rniecestro@estherapeutics.com., Foster EC; Department of Neuroscience, The School of Translational Medicine, Monash University, Melbourne, VIC, 3004, Australia.; Department of Neurology, Alfred Health, Commercial Road, Melbourne, VIC, 3000, Australia., Millist L; Department of Neuroscience, The School of Translational Medicine, Monash University, Melbourne, VIC, 3004, Australia., Germaine J; Department of Neuroscience, The School of Translational Medicine, Monash University, Melbourne, VIC, 3004, Australia., Niecestro A; ES-Therapeutics, New York, NY, USA., O'Brien TJ; Department of Neuroscience, The School of Translational Medicine, Monash University, Melbourne, VIC, 3004, Australia.; Department of Neurology, Alfred Health, Commercial Road, Melbourne, VIC, 3000, Australia. |
| Source: | European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2026 Jan; Vol. 51 (1), pp. 97-109. Date of Electronic Publication: 2026 Jan 05. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial |
| Journal Info: | Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2107-0180 |
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| DOI: | 10.1007/s13318-025-00979-8 |
